SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A5GCZ8

- GCSPA_GEOUR

UniProt

A5GCZ8 - GCSPA_GEOUR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene
gcvPA, Gura_0337
Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciGURA351605:GI6A-343-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1 (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein subunit 1
Glycine decarboxylase subunit 1
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Gene namesi
Name:gcvPA
Ordered Locus Names:Gura_0337
OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Taxonomic identifieri351605 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000006695: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 442442Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotationPRO_1000083222Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity.

Protein-protein interaction databases

STRINGi351605.Gura_0337.

Structurei

3D structure databases

ProteinModelPortaliA5GCZ8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OMAiLPMHASE.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

A5GCZ8-1 [UniParc]FASTAAdd to Basket

« Hide

MSYCPNTPED IREMLAAIGV ASVDALFAPI PAGLRARSFA LPDGTSEQEL    50
LRQMKQLAGT DRPVTGFIGG GYYDHYIPAV VDHLSGRAEF YTAYTPYQPE 100
CSQGTLQALF EYQTAICRLT GMEVSNASLY DGGTALAEAA MMALRVTGRN 150
RLVIDGSVNP FSREIVRTYL TNLGVEIVEI PARDGLADRP ALTAALTDLT 200
AAVILQNPNF FGSVEDLSDI ALTAHANGAL LIASVYPISL GLVKSPGAMG 250
ADIVVGDGQS LGNPLSFGGP SFGFIATTKK YIRNLPGRII GETVDKSGRR 300
GFVLTLQARE QHIKRHKATS NICSNQSLCA LRGMIFLASV GKEGLVDLAR 350
LNRDKAEYAK GLLGSIKGVK LLNTAPTFNE FTIVLPKDAA EVAERLLGKG 400
VAAGVPLGAY YHGMDNCLVV TVTEKRTRDE IDALAKELEG AL 442
Length:442
Mass (Da):47,142
Last modified:June 12, 2007 - v1
Checksum:i7E815ADAE2A70EEF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000698 Genomic DNA. Translation: ABQ24553.1.
RefSeqiWP_011937279.1. NC_009483.1.
YP_001229126.1. NC_009483.1.

Genome annotation databases

EnsemblBacteriaiABQ24553; ABQ24553; Gura_0337.
GeneIDi5165879.
KEGGigur:Gura_0337.
PATRICi22030512. VBIGeoUra13052_0352.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000698 Genomic DNA. Translation: ABQ24553.1 .
RefSeqi WP_011937279.1. NC_009483.1.
YP_001229126.1. NC_009483.1.

3D structure databases

ProteinModelPortali A5GCZ8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351605.Gura_0337.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ24553 ; ABQ24553 ; Gura_0337 .
GeneIDi 5165879.
KEGGi gur:Gura_0337.
PATRICi 22030512. VBIGeoUra13052_0352.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OMAi LPMHASE.
OrthoDBi EOG6XWV3B.

Enzyme and pathway databases

BioCyci GURA351605:GI6A-343-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rf4.

Entry informationi

Entry nameiGCSPA_GEOUR
AccessioniPrimary (citable) accession number: A5GCZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: September 3, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi