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A5GAW4

- EFTU_GEOUR

UniProt

A5GAW4 - EFTU_GEOUR

Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    • Comment

    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciGURA351605:GI6A-1066-MONOMER.
    GURA351605:GI6A-1080-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf1UniRule annotation
    Ordered Locus Names:Gura_1053
    AND
    Name:tuf2UniRule annotation
    Ordered Locus Names:Gura_1066
    OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
    Taxonomic identifieri351605 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000006695: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 396396Elongation factor TuPRO_0000337396Add
    BLAST

    Proteomic databases

    PRIDEiA5GAW4.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi351605.Gura_1066.

    Structurei

    3D structure databases

    ProteinModelPortaliA5GAW4.
    SMRiA5GAW4. Positions 2-395.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 206197tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni60 – 645G2By similarity
    Regioni81 – 844G3By similarity
    Regioni136 – 1394G4By similarity
    Regioni174 – 1763G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiERKPHIN.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5GAW4-1 [UniParc]FASTAAdd to Basket

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    MAKAKFERTK PHVNIGTIGH VDHGKTTLTA AITKVLAGKG QAEFKAFDQI    50
    DNAPEERERG ITIATAHVEY ETDKRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVVSAAD GPMPQTREHI LLARQVGVPY IVVFLNKADM VDDEELLELV 150
    ELEIRELLSS YDFPGDDIPI IKGSALKALE GDTGELGEQA IMKLMEAVDS 200
    YIPEPVRAID KPFLMPVEDV FSISGRGTVA TGRVERGIVK VGEEVEIVGM 250
    KATAKTTVTG VEMFRKLLDE GRAGDNIGAL LRGVKREDIE RGQVLAKPGS 300
    ITPHTKFKAE AYILTKEEGG RHTPFFNGYR PQFYFRTTDV TGIVELAAGT 350
    EMVMPGDNVA VTVNLITPIA MDEGLRFAIR EGGRTVGAGV VSSIIE 396
    Length:396
    Mass (Da):42,998
    Last modified:June 12, 2007 - v1
    Checksum:iC339BDA315691A3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000698 Genomic DNA. Translation: ABQ25259.1.
    CP000698 Genomic DNA. Translation: ABQ25272.1.
    RefSeqiYP_001229832.1. NC_009483.1.
    YP_001229845.1. NC_009483.1.

    Genome annotation databases

    EnsemblBacteriaiABQ25259; ABQ25259; Gura_1053.
    ABQ25272; ABQ25272; Gura_1066.
    GeneIDi5162890.
    5166003.
    KEGGigur:Gura_1053.
    gur:Gura_1066.
    PATRICi22032078. VBIGeoUra13052_1128.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000698 Genomic DNA. Translation: ABQ25259.1 .
    CP000698 Genomic DNA. Translation: ABQ25272.1 .
    RefSeqi YP_001229832.1. NC_009483.1.
    YP_001229845.1. NC_009483.1.

    3D structure databases

    ProteinModelPortali A5GAW4.
    SMRi A5GAW4. Positions 2-395.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 351605.Gura_1066.

    Proteomic databases

    PRIDEi A5GAW4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ25259 ; ABQ25259 ; Gura_1053 .
    ABQ25272 ; ABQ25272 ; Gura_1066 .
    GeneIDi 5162890.
    5166003.
    KEGGi gur:Gura_1053.
    gur:Gura_1066.
    PATRICi 22032078. VBIGeoUra13052_1128.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ERKPHIN.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci GURA351605:GI6A-1066-MONOMER.
    GURA351605:GI6A-1080-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rf4.

    Entry informationi

    Entry nameiEFTU_GEOUR
    AccessioniPrimary (citable) accession number: A5GAW4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3