A5G8G3 (CYSD_GEOUR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	Gura_3934

Organism

Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens) [Complete proteome] [HAMAP]

Taxonomic identifier

351605 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	301 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.
Sequence caution	The sequence ABQ28081.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 301	301	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340195

Sequences

	Sequence		Length	Mass (Da)
	A5G8G3 [UniParc]. Last modified June 10, 2008. Version 2. Checksum: 9323E0F4AA238DF9	FASTA	301	34,800
	10 20 30 40 50 60 MNGTLTHLQQ LEAESIHIIR EVVAEFANPV MLYSIGKDSA VMLHLARKAF FPAPPPFPLL 70 80 90 100 110 120 HVDTTWKFRE MIQFRDRMAA ECGLDLIVHV NEEGVKNGIS PFTHGSALYT DVMKTEGLKQ 130 140 150 160 170 180 ALDKYKFDAA FGGARRDEEK SRAKERIFSF RCTNHRWDPK NQRPELWNLY NTRIKPGESI 190 200 210 220 230 240 RVFPLSNWTE LDVWQYIHLE NIPIVPLYYA AVRPVVERDG MLIMVDDERL ELKPGEKVQY 250 260 270 280 290 300 KSVRFRTLGC YPLTGAVEST ADTLPQIIQE MLLTRTSERQ GRLIDHDQDG SMEKKKQEGY F

References

[1]

"Complete sequence of Geobacter uraniireducens Rf4." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Shelobolina E., Aklujkar M., Lovley D., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Rf4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000698 Genomic DNA. Translation: ABQ28081.1. Different initiation.
RefSeq	YP_001232654.1. NC_009483.1.
3D structure databases
ProteinModelPortal	A5G8G3.
SMR	A5G8G3. Positions 1-211.
ModBase	Search...
Protein-protein interaction databases
STRING	A5G8G3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5165118.
GenomeReviews	Gene locus Gura_3934 in contig CP000698_GR.
KEGG	gur:Gura_3934.
NMPDR	fig|351605.3.peg.618.
PATRIC	22038303. VBIGeoUra13052_4199.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	GURA351605:GURA_3934-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_GEOUR

Accession

Primary (citable) accession number: A5G8G3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 33 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program