Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanine racemase

Gene

Gura_3850

Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (Gura_3850)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei45Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei143SubstrateUniRule annotation1
Active sitei275Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei323Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Gura_3850Imported
OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)Imported
Taxonomic identifieri351605 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000006695 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei45N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi351605.Gura_3850

Structurei

3D structure databases

ProteinModelPortaliA5G882
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini254 – 383Ala_racemase_CInterPro annotationAdd BLAST130

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
HOGENOMiHOG000031444
KOiK01775
OMAiWEILCGF
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 2 hits
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

A5G882-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERLNVLNLD SRPTIAEIDL AALRHNYYQV KKAVPAGSGL LAVVKADAYG
60 70 80 90 100
HGFMDISREL EALGVTAFGV AFLAEGIQLR KSGIDRPILL LGGIYPGQEK
110 120 130 140 150
KCVGFNISTA VFSLDQARVL DDVARKLYRK AKIHLKVDTG MGRLGIRYEE
160 170 180 190 200
APAFFRELKK LKNLELEGIF SHFASADELD DEGSGYTARQ TEIFAAVLQE
210 220 230 240 250
GTRQGFSPTF VHIANSAAAF SRDFPFCNLA RPGIVLYGAL PSADFQGKID
260 270 280 290 300
VKPVMRLKSR VAMLKWVEPG TSISYARRYV AGKKTLVASV PVGYADGYCR
310 320 330 340 350
ALTNKGEALV RGQRARVAGT VCMDWIMLDV TDIAGVAVGD EVTLLGCDNQ
360 370 380
GNCIHAEELA AWSGTIAYEI FCGISKRVPR VYIP
Length:384
Mass (Da):41,874
Last modified:June 12, 2007 - v1
Checksum:iB86560FE305BFBD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000698 Genomic DNA Translation: ABQ28000.1

Genome annotation databases

EnsemblBacteriaiABQ28000; ABQ28000; Gura_3850
KEGGigur:Gura_3850

Similar proteinsi

Entry informationi

Entry nameiA5G882_GEOUR
AccessioniPrimary (citable) accession number: A5G882
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: February 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health