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A5G882

- A5G882_GEOUR

UniProt

A5G882 - A5G882_GEOUR

Protein

Alanine racemase

Gene

Gura_3850

Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei45 – 451Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei143 – 1431SubstrateUniRule annotation
    Active sitei275 – 2751Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei323 – 3231Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciGURA351605:GI6A-3902-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Gura_3850Imported
    OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)Imported
    Taxonomic identifieri351605 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000006695: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei45 – 451N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi351605.Gura_3850.

    Structurei

    3D structure databases

    ProteinModelPortaliA5G882.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiRIGISIY.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5G882-1 [UniParc]FASTAAdd to Basket

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    MERLNVLNLD SRPTIAEIDL AALRHNYYQV KKAVPAGSGL LAVVKADAYG    50
    HGFMDISREL EALGVTAFGV AFLAEGIQLR KSGIDRPILL LGGIYPGQEK 100
    KCVGFNISTA VFSLDQARVL DDVARKLYRK AKIHLKVDTG MGRLGIRYEE 150
    APAFFRELKK LKNLELEGIF SHFASADELD DEGSGYTARQ TEIFAAVLQE 200
    GTRQGFSPTF VHIANSAAAF SRDFPFCNLA RPGIVLYGAL PSADFQGKID 250
    VKPVMRLKSR VAMLKWVEPG TSISYARRYV AGKKTLVASV PVGYADGYCR 300
    ALTNKGEALV RGQRARVAGT VCMDWIMLDV TDIAGVAVGD EVTLLGCDNQ 350
    GNCIHAEELA AWSGTIAYEI FCGISKRVPR VYIP 384
    Length:384
    Mass (Da):41,874
    Last modified:June 12, 2007 - v1
    Checksum:iB86560FE305BFBD2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000698 Genomic DNA. Translation: ABQ28000.1.
    RefSeqiYP_001232573.1. NC_009483.1.

    Genome annotation databases

    EnsemblBacteriaiABQ28000; ABQ28000; Gura_3850.
    GeneIDi5166061.
    KEGGigur:Gura_3850.
    PATRICi22038119. VBIGeoUra13052_4108.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000698 Genomic DNA. Translation: ABQ28000.1 .
    RefSeqi YP_001232573.1. NC_009483.1.

    3D structure databases

    ProteinModelPortali A5G882.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 351605.Gura_3850.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ28000 ; ABQ28000 ; Gura_3850 .
    GeneIDi 5166061.
    KEGGi gur:Gura_3850.
    PATRICi 22038119. VBIGeoUra13052_4108.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi RIGISIY.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci GURA351605:GI6A-3902-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rf4Imported.

    Entry informationi

    Entry nameiA5G882_GEOUR
    AccessioniPrimary (citable) accession number: A5G882
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 12, 2007
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3