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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei351 – 3511UniRule annotation
Active sitei455 – 4551UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciGURA351605:GI6A-3803-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Gura_3752
OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Taxonomic identifieri351605 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000006695: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 530530Glucose-6-phosphate isomerasePRO_1000135531Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351605.Gura_3752.

Structurei

3D structure databases

ProteinModelPortaliA5G7Y7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5G7Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKLHLWERY KSHLNVNPAI GLMLDISRMD FPDGFFNDIE QRMQKAFNDM
60 70 80 90 100
AELEGGAIAN QDERRMVGHY WLREPNLAPT GGLAAEIAFT LRGIKEFAAG
110 120 130 140 150
VHDGTVTAPT GKRFMRMLVV GIGGSALGPQ FVADALGSAA DRLRPYFFDN
160 170 180 190 200
TDPDGMDRVL AEIGASLRET MTIVISKSGG TKETRNGMLE AKRAYHAMGL
210 220 230 240 250
EFAEHAVAVT GKDSELDKTA VREGWLARFP MWDWVGGRTS VTSAVGLLPA
260 270 280 290 300
ALQGIDIAAL LEGARLCDEI TRGRETRANP AALLALMWHH ATAGRGAKDM
310 320 330 340 350
VILPYKDRLL LFSRYLQQLI MESIGKERDL DGNIVNQGIA VYGNKGSTDQ
360 370 380 390 400
HAYVQQLREG VNNFFVTFIE VLQDREGKSM EVEAGVTSGD YLNGFFQGTR
410 420 430 440 450
QALYENGRES LTITVDRLDA RTIGALIALY ERAVGYYASL VNINAYHQPG
460 470 480 490 500
VEAGKKAAGV VLNLQGEVLS YLHRAQGMEF TAEEMAAAIG AEKEVETVFK
510 520 530
ILLHASANPG HGIAREAGET VFDWRFRSVR
Length:530
Mass (Da):58,219
Last modified:June 12, 2007 - v1
Checksum:i90D44ADF2DC5F50A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000698 Genomic DNA. Translation: ABQ27905.1.
RefSeqiYP_001232478.1. NC_009483.1.

Genome annotation databases

EnsemblBacteriaiABQ27905; ABQ27905; Gura_3752.
GeneIDi5163133.
KEGGigur:Gura_3752.
PATRICi22037916. VBIGeoUra13052_4007.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000698 Genomic DNA. Translation: ABQ27905.1.
RefSeqiYP_001232478.1. NC_009483.1.

3D structure databases

ProteinModelPortaliA5G7Y7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351605.Gura_3752.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ27905; ABQ27905; Gura_3752.
GeneIDi5163133.
KEGGigur:Gura_3752.
PATRICi22037916. VBIGeoUra13052_4007.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciGURA351605:GI6A-3803-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Rf4.

Entry informationi

Entry nameiG6PI_GEOUR
AccessioniPrimary (citable) accession number: A5G7Y7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 12, 2007
Last modified: March 4, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.