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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGURA351605:G1G8X-2382-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Gura_2304
OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Taxonomic identifieri351605 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000006695 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000762161 – 561Arginine--tRNA ligaseAdd BLAST561

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi351605.Gura_2304

Structurei

3D structure databases

ProteinModelPortaliA5G3W5
SMRiA5G3W5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi129 – 139"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A5G3W5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKELLRDLIT KELASCFADG SLSSGVFPSI VIEKPAHAEH GDFATNVAML
60 70 80 90 100
LAKAEKKAPR VVAEILVSRL QESADICSKL EVAGPGFINF YVKDEAWRQT
110 120 130 140 150
LIAIDRACAD YGKSRIGEGK KIQVEFVSAN PTGPLHIGHG RGAAIGDTIC
160 170 180 190 200
RLLAAIGWDV TREFYYNDAG QQIANLALSV QARCLGIEPD DPRWPLDGYQ
210 220 230 240 250
GDYIRDVARS YLGQETVEAD DQHVTAAGDP QDLDAIRRFA VAYLRREQDQ
260 270 280 290 300
DLTAFDVHFD VYSLESALYA EGRVEAVVQR LIDSGHTYEQ DGALWLRTTT
310 320 330 340 350
FGDDKDRVMR KADGGYTYFV PDVAYHLSKW ERGFTRVINE QGADHHSTIT
360 370 380 390 400
RVRAGLQALN AGIPVGWPEY VLHQMVTVMR GGEEVKISKR AGSYVTLRDL
410 420 430 440 450
IDEVGRDATR FFFVMRKPDS QLVFDIDLAK QQTLDNPVYY VQYAHARICS
460 470 480 490 500
IFENALERGF VLPAAESVPL ERLVTLEEMT IIKTLASFPE ILEGSALNFE
510 520 530 540 550
PHRVTYYLQE LAGQFHSFYN RNRVITEDAE LTAARLFLLK CVALTLKNAL
560
TVLGISAPEK M
Length:561
Mass (Da):62,651
Last modified:June 12, 2007 - v1
Checksum:iE0262C1DD274788B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000698 Genomic DNA Translation: ABQ26483.1
RefSeqiWP_011939177.1, NC_009483.1

Genome annotation databases

EnsemblBacteriaiABQ26483; ABQ26483; Gura_2304
KEGGigur:Gura_2304

Similar proteinsi

Entry informationi

Entry nameiSYR_GEOUR
AccessioniPrimary (citable) accession number: A5G3W5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome