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A5G382

- PGK_GEOUR

UniProt

A5G382 - PGK_GEOUR

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381SubstrateUniRule annotation
    Binding sitei120 – 1201SubstrateUniRule annotation
    Binding sitei153 – 1531SubstrateUniRule annotation
    Binding sitei204 – 2041ATPUniRule annotation
    Binding sitei326 – 3261ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi352 – 3554ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciGURA351605:GI6A-2087-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:Gura_2060
    OrganismiGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens)
    Taxonomic identifieri351605 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000006695: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 399399Phosphoglycerate kinasePRO_1000076589Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi351605.Gura_2060.

    Structurei

    3D structure databases

    ProteinModelPortaliA5G382.
    SMRiA5G382. Positions 5-396.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni22 – 243Substrate bindingUniRule annotation
    Regioni61 – 644Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiMSIRYID.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5G382-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIRYIDEIS DLREKKIFMR VDFNVPLDEH QNITEDTRIR AVLPTINYAL    50
    DYNAKVVLAS HLGRPKGERN AKYSMAPAAK RLSRLLGKEV KLAPDCIGDG 100
    VSKIIDSMQP GDVVMLENLR FYPGEEKNDD DFAKALADHC DIYVNDAFAV 150
    SHRAHASVEA ITKFFPIVAA GFLMKNEMSY FEKSMKNPIR PLVAILGGAK 200
    VSGKLEVLEN LCNKVDKVII GGGMAFTFLK ALGYNVGKSL VEENLLETAL 250
    NTYNKAREKG IKFYLPVDCV VADQFNPAAE TKVTTIQEIP EGWMALDIGP 300
    ATVTLFSTAL QNAKTIVWNG PMGVFEMDAF SRGTFAMVSA VANSYALTIV 350
    GGGDTDVAVH RAGEYAKISY ISTGGGAFLE LLEGKKLPGI KVLEDNGHK 399
    Length:399
    Mass (Da):43,653
    Last modified:June 12, 2007 - v1
    Checksum:iB62D5C220C4E795B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000698 Genomic DNA. Translation: ABQ26250.1.
    RefSeqiWP_011938952.1. NC_009483.1.
    YP_001230823.1. NC_009483.1.

    Genome annotation databases

    EnsemblBacteriaiABQ26250; ABQ26250; Gura_2060.
    GeneIDi5165408.
    KEGGigur:Gura_2060.
    PATRICi22034250. VBIGeoUra13052_2200.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000698 Genomic DNA. Translation: ABQ26250.1 .
    RefSeqi WP_011938952.1. NC_009483.1.
    YP_001230823.1. NC_009483.1.

    3D structure databases

    ProteinModelPortali A5G382.
    SMRi A5G382. Positions 5-396.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 351605.Gura_2060.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ26250 ; ABQ26250 ; Gura_2060 .
    GeneIDi 5165408.
    KEGGi gur:Gura_2060.
    PATRICi 22034250. VBIGeoUra13052_2200.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi MSIRYID.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci GURA351605:GI6A-2087-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Rf4.

    Entry informationi

    Entry nameiPGK_GEOUR
    AccessioniPrimary (citable) accession number: A5G382
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3