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Protein

60 kDa chaperonin

Gene

groL

Organism
Acidiphilium cryptum (strain JF-5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Acry_2503
OrganismiAcidiphilium cryptum (strain JF-5)
Taxonomic identifieri349163 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcidiphilium
Proteomesi
  • UP000000245 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000257451 – 54960 kDa chaperoninAdd BLAST549

Proteomic databases

PRIDEiA5G1G2.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi349163.Acry_2503.

Structurei

3D structure databases

ProteinModelPortaliA5G1G2.
SMRiA5G1G2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A5G1G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVRFSA DARERLIRGV DLLANAVKVT LGPKGRNVVI EKSFGSPRIT
60 70 80 90 100
KDGVTVAKEI ELADKFENMG AQMVREVASK TNDLAGDGTT TATVLAQAIV
110 120 130 140 150
REGAKAVAAG MNPMDLKRGI DKAVNAIVDE LKKRTKKITT PSETAQVGTI
160 170 180 190 200
SANGEAEIGK MISEAMQKVG NEGVITVEEA KGIQTELDVV EGMQFDRGYV
210 220 230 240 250
SPYFITNPEK MVADLDNPYI LIHEKKLSGL QPMLPLLESI VQSGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKIAAVKAPG FGDRRKAMLE DIAILTGGQV
310 320 330 340 350
ISEDLGIKLE TVTLNMLGRA KKVLIEKENT TIVEGAGKKA DITGRCNQIR
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGASETEVK ERKDRVDDAL
410 420 430 440 450
HATRAAVEEG IVPGGGVALA RASLAINKLK ADNDDQRFGI DIIRKAVLAP
460 470 480 490 500
MRQIAENAGE DGAVISGKVL DNDDYSFGFD AQSGEFKDMV KAGIIDPTKV
510 520 530 540
VRTALQDAAS VAGLLITTEA MVAERPEKKA PAGGDAGMGG MGGMGGMDF
Length:549
Mass (Da):58,230
Last modified:June 12, 2007 - v1
Checksum:iA2D700BB9A8F42EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000697 Genomic DNA. Translation: ABQ31694.1.
RefSeqiWP_007423234.1. NC_009484.1.

Genome annotation databases

EnsemblBacteriaiABQ31694; ABQ31694; Acry_2503.
KEGGiacr:Acry_2503.

Similar proteinsi

Entry informationi

Entry nameiCH60_ACICJ
AccessioniPrimary (citable) accession number: A5G1G2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: June 7, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families