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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Acidiphilium cryptum (strain JF-5)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotation
Gene namesi
Name:clpBUniRule annotation
Ordered Locus Names:Acry_1823Imported
OrganismiAcidiphilium cryptum (strain JF-5)Imported
Taxonomic identifieri349163 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcidiphilium
Proteomesi
  • UP000000245 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiA5FZJ3

Interactioni

Subunit structurei

Homohexamer. The oligomerization is ATP-dependent.SAAS annotation
Homohexamer; The oligomerization is ATP-dependent.UniRule annotation

Protein-protein interaction databases

STRINGi349163.Acry_1823

Structurei

3D structure databases

ProteinModelPortaliA5FZJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini199 – 344AAAInterPro annotationAdd BLAST146
Domaini594 – 738AAAInterPro annotationAdd BLAST145
Domaini763 – 852ClpB_D2-smallInterPro annotationAdd BLAST90

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili435 – 462UniRule annotationAdd BLAST28

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilUniRule annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C2Z Bacteria
COG0542 LUCA
HOGENOMiHOG000218211
KOiK03695
OMAiHDKFLPD
OrthoDBiPOG091H019M

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR017730 Chaperonin_ClpB
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR028299 ClpA/B_CS2
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF02861 Clp_N, 2 hits
PF10431 ClpB_D2-small, 1 hit
PRINTSiPR00300 CLPPROTEASEA
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit
TIGRFAMsiTIGR03346 chaperone_ClpB, 1 hit
PROSITEiView protein in PROSITE
PS00870 CLPAB_1, 1 hit
PS00871 CLPAB_2, 1 hit

Sequencei

Sequence statusi: Complete.

A5FZJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFEKFTERA RGFVQAAQTI AVREYHQQIT PEHLLKAFLD DEEGAASGLI
60 70 80 90 100
RAAGGDPAAV RLAADAAIGK LPKVQGSGAG QPQITPDLVR VLDAAQQMAQ
110 120 130 140 150
KAGDEYVAQD RVLVALAASG TPAGRALTAA GASAQALEKA VADIRKGRTV
160 170 180 190 200
TSANAEQTFD ALKKYARDVT EAARAQKLDP VIGRDEEIRR AIQVLARRTK
210 220 230 240 250
NNPVLIGEPG VGKTAIVEGL ALRIVNGDVP EALKGKRLLA LDLGAMVAGA
260 270 280 290 300
KYRGEFEERL KAVLKEIEGS NGEVILFIDE MHTLVGAGRA DGAMDASNLI
310 320 330 340 350
KPELARGALH CVGATTLDEY RKYIEKDAAL ARRFQPVFVD EPSVEDTISI
360 370 380 390 400
LRGIKEKYEL HHGVRISDSA LVAAATLSNR YITDRFLPDK AIDLVDEAAS
410 420 430 440 450
RLRMQVDSKP EALDELDRRL MQLKIEREAL RKEQDPASKE RLERLEGEIA
460 470 480 490 500
ELEEKSDAMT AAWKAEKDRL NATQKLKEQL DQARGEAEMA QRSGNLTRAS
510 520 530 540 550
ELMYGVIPEI ERKLAAGPTE GAMVNEAVTE AQIAQVVARW TGIPVDRMLE
560 570 580 590 600
GERAKLIRME EELRKRVVGQ EAALRAVSDA VRRARAGLQD PNRPIGSFLF
610 620 630 640 650
LGPTGVGKTE TCKALAEFLF DDERAMVRID MSEFMEKHAV ARLIGAPPGY
660 670 680 690 700
VGYEEGGVLT EAVRRRPYQV ILFDEVEKAH EDVFNVLLQV LDDGRLTDGQ
710 720 730 740 750
GRTVDFKNTI IVLTSNLGSE VLAAQPEGED VVLAEPQVMR VVRQHFRPEF
760 770 780 790 800
LNRLDEIILF RRLQRADMAR IVEIQLRHLE SLLADRKITL HLDQAARDWL
810 820 830 840 850
ANEGYDPVYG ARPLKRVIQR SLQNKLATRL LEGAIHDGET VNVTIDDDGL
860
SIAGGLAAAA
Length:860
Mass (Da):94,391
Last modified:June 12, 2007 - v1
Checksum:iFFC359C8A27AD61F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000697 Genomic DNA Translation: ABQ31025.1
RefSeqiWP_011942516.1, NC_009484.1

Genome annotation databases

EnsemblBacteriaiABQ31025; ABQ31025; Acry_1823
KEGGiacr:Acry_1823

Similar proteinsi

Entry informationi

Entry nameiA5FZJ3_ACICJ
AccessioniPrimary (citable) accession number: A5FZJ3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health