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A5FXX2 (A5FXX2_ACICJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate synthase G HAMAP MF_00641 RuleBase RU003572
EC=2.3.3.9 HAMAP MF_00641 RuleBase RU003572
Gene names
Name:glcB HAMAP MF_00641
Ordered Locus Names:Acry_1243
OrganismAcidiphilium cryptum (strain JF-5) [Complete proteome] [HAMAP]
Taxonomic identifier349163 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Acidiphilium

Protein attributes

Sequence length722 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641 RuleBase RU003572 SAAS SAAS006253

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641 RuleBase RU003572 SAAS SAAS006253

Subunit structure

Monomer By similarity. HAMAP MF_00641 SAAS SAAS006253

Subcellular location

Cytoplasm By similarity HAMAP MF_00641 RuleBase RU003572.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily. HAMAP MF_00641 RuleBase RU003572

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site3401Proton acceptor By similarity HAMAP MF_00641
Active site6311Proton donor By similarity HAMAP MF_00641

Sequences

Sequence LengthMass (Da)Tools
A5FXX2 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: F517E5EC117F2490

FASTA72278,017
        10         20         30         40         50         60 
MSQTYVDAAG LRVAAELHQF IETEALPGTG VESGAFWQGF AGLIARHAPR NAELLAERDR 

        70         80         90        100        110        120 
LQAAIDDWHR SRRGQPVDPA AYEAFLREIG YLRPEPGDVK VTSERVDPEI AAIAGPQLVV 

       130        140        150        160        170        180 
PVMNARYALN AANARWGSLY DALYGTDAIP ESGGLERGKA YNPQRGAAVV ARGRAFLDDH 

       190        200        210        220        230        240 
FPLATGSHAD VRAWRVHNGH LAAVLESGET GLKHAAQFAG YRGEPAAPTA VLLRHHNLHV 

       250        260        270        280        290        300 
EIAIDPTSPI GRTDKAGVAD LIVESAISTI MDAEDSVAAV DAEDKVLVYR NWLGLMAGTL 

       310        320        330        340        350        360 
SEQVEKGGKT FTRALNPDRA YTAPDGSTLT LPGRVLMLVR NVGHHIYTDT VLDAAGKPIP 

       370        380        390        400        410        420 
ETILDLVVTS LCGLHDIRRT AGLRNSRAGS VYIVKPKMHG ADEVAYANGL FAATESLLGL 

       430        440        450        460        470        480 
APDTLKMGIM DEERRTSANL KACIAAAASR IFFINTGFLD RTGDEIHTSI EAGPMIRKNE 

       490        500        510        520        530        540 
IRNTPWIKAY EDRNVDIGIV CGLPGHAQIG KGMWAAPDAM AAMLEQKVGH PRAGANTAWV 

       550        560        570        580        590        600 
PSPTAATLHA LHYHMVDVAA RQAELAARPM GSLADLLTIP LADRPNWRPE DIQQELDNNA 

       610        620        630        640        650        660 
QGILGYVVRW IDQGIGCSKV PDIHNVALME DRATLRISAQ HIANWLHHGI VSEAQVMETM 

       670        680        690        700        710        720 
KRMAAVVDGQ NAGDPAYRNM APGFDGVAFQ AACDLVFKGR TQPNGYTEFI LHDRRREAKA 


SA

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References

[1]"Complete sequence of chromosome of Acidiphilium cryptum JF-5."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Magnuson T., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JF-5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000697 Genomic DNA. Translation: ABQ30454.1.
RefSeqYP_001234373.1. NC_009484.1.

3D structure databases

ProteinModelPortalA5FXX2.
SMRA5FXX2. Positions 1-721.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5FXX2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5159785.
GenomeReviewsGene locus Acry_1243 in contig CP000697_GR.
KEGGacr:Acry_1243.
PATRIC20647488. VBIAciCry6074_1734.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2225.
HOGENOMHBG350005.
ProtClustDBPRK02999.

Family and domain databases

HAMAPMF_00641. Malate_synth_G.
[Tree]
InterProIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
Gene3DG3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
KOK01638.
PANTHERPTHR21631:SF1. Malate_synthase. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01345. Malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5FXX2_ACICJ
AccessionPrimary (citable) accession number: A5FXX2
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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