A5FX76 (A5FX76_ACICJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Choline dehydrogenase RuleBase RU003969
EC=1.1.99.1 RuleBase RU003969

Gene names

Ordered Locus Names:

Acry_0991

Organism

Acidiphilium cryptum (strain JF-5) [Complete proteome] [HAMAP]

Taxonomic identifier

349163 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Acidiphilium

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. RuleBase RU003969 SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867 RuleBase RU003968
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. RuleBase RU003969 SAAS SAAS007867
Sequence similarities	Belongs to the GMC oxidoreductase family. RuleBase RU003968

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533 RuleBase RU003968
Molecular function	Oxidoreductase SAAS SAAS007867 EMBL ABQ30208.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5FX76 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 823B35FA59788E5A	FASTA	552	61,129
	10 20 30 40 50 60 MPSEYDYIIV GAGSAGCAMA NRLTEDGNAT VLLLEFGGSD RSPFIQMPSA LSIPMNTRKY 70 80 90 100 110 120 DWGYHSEPEP HLGGRRMHTP RGKVLGGSSS INGLVYIRGN AMDFEHWEEM GARGWGWRDV 130 140 150 160 170 180 LPYFRRAETR AEGGDAYRGD SGPLHTSYGR LANPLYRAFI EAGRQAGYPV TDDVNGYQQE 190 200 210 220 230 240 GFGRMDMTVH RGRRWSTANA YLRPIRNRPN LTLHARSLVS HIVFAGKAAS GVAYRRFGQD 250 260 270 280 290 300 IVARARREVI LAAGAINSPQ LLKRSGIGPA AELAALGIDV VADRPGVGEN LQDHLEFYFQ 310 320 330 340 350 360 VACTRPITLY SAMNPLAKAM IGLRWLLFHD GLGATNHFES CGFIRSRPGV EYPDIQYHFL 370 380 390 400 410 420 PVAIRYDGRA HATQHGFQAH VGPMRSNSRG WVRLRDRNPA TPPRIFFNYM SEKQDWADMR 430 440 450 460 470 480 ACVRLTREIF AQEAFAPFRG AEIAPGADVT TDAEIDAFIR GAVESAYHPS GTCRMGDAAD 490 500 510 520 530 540 PLAVVDPETR VIGVERLRVA DSSIMPRITN GNLNAPTIMI GEKAADHIRG RDPLPPSNAP 550 FHRAERWQTA QR

References

[1]

"Complete sequence of chromosome of Acidiphilium cryptum JF-5." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Magnuson T., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JF-5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000697 Genomic DNA. Translation: ABQ30208.1.
RefSeq	YP_001234127.1. NC_009484.1.
3D structure databases
ProteinModelPortal	A5FX76.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FX76.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5161606.
GenomeReviews	Gene locus Acry_0991 in contig CP000697_GR.
KEGG	acr:Acry_0991.
PATRIC	20646978. VBIAciCry6074_1483.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	RSTAPYY.
ProtClustDB	CLSK971246.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5FX76_ACICJ

Accession

Primary (citable) accession number: A5FX76

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)