Reviewed, UniProtKB/Swiss-Prot A5FWQ4 (GLMM_ACICJ)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Acry_0817

Organism

Acidiphilium cryptum (strain JF-5) [Complete proteome] [HAMAP]

Taxonomic identifier

349163 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Acidiphilium

Protein attributes

Sequence length	456 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 456	456	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000318616
Sites
	Active site	109	1	Phosphoserine intermediate By similarity
	Metal binding	109	1	Magnesium; via phosphate group By similarity
	Metal binding	250	1	Magnesium By similarity
	Metal binding	252	1	Magnesium By similarity
	Metal binding	254	1	Magnesium By similarity
Amino acid modifications
	Modified residue	109	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5FWQ4-1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 6D6298EA9A5A8EC6	FASTA	456	47,614
	10 20 30 40 50 60 MNQIQPRPKR RLFGTDGIRG RANTAPMTAE IALRLGQAAG LLFTRGDHRH RVIIGKDTRL 70 80 90 100 110 120 SGYMLEPALT AGFIGAGMDV TLAGPLPTPA IAMLTRSLRA DLGVVISASH NPFEDNGIKL 130 140 150 160 170 180 FGPDGAKLSD ETEAEIEALM EEDLSGRLAA PSALGRAMRL VDAAGRYVES AKSSLPRGLR 190 200 210 220 230 240 LDGLRVVLDC ANGAAYKVAP AALWELGAEV ITLGVSPDGF NINHECGSTV PSALSAAVVK 250 260 270 280 290 300 HRADLGIALD GDADRVILAD ERGRIIDGDQ VLALIARAFQ ADGRLSGSGI VATVMSNLGL 310 320 330 340 350 360 ERYLGGLGLA LHRTPVGDRY VAEHMRAHGL NLGGEQSGHV ILADFATTGD GLIAALQVLA 370 380 390 400 410 420 VLVREGRPAS EVCRLFTPLP QLLRNVRYSG ASPLLSPAVT AAAAAAEARL AGIGRLLLRA 430 440 450 SGTEPLIRVM AEGEDEQLVA AVVDELCAVI EAESAG

References

[1]

"Complete sequence of chromosome of Acidiphilium cryptum JF-5." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Magnuson T., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000697 Genomic DNA. Translation: ABQ30036.1.
RefSeq	YP_001233955.1.
3D structure databases
SMR	A5FWQ4. Positions 10-452.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FWQ4.
Genome annotation databases
GeneID	5161695.
GenomeReviews	Gene locus Acry_0817 in contig CP000697_GR.
KEGG	acr:Acry_0817.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 1 hit.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACICJ

Accession

Primary (citable) accession number: A5FWQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	June 12, 2007
Last modified:	January 19, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)