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A5FUM6

- PQQC_ACICJ

UniProt

A5FUM6 - PQQC_ACICJ

Protein

Pyrroloquinoline-quinone synthase

Gene

pqqC

Organism
Acidiphilium cryptum (strain JF-5)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    Functioni

    Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.UniRule annotation

    Catalytic activityi

    6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. pyrroloquinoline-quinone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyrroloquinoline quinone biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    PQQ biosynthesis

    Enzyme and pathway databases

    BioCyciACRY349163:GHET-81-MONOMER.
    UniPathwayiUPA00539.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyrroloquinoline-quinone synthaseUniRule annotation (EC:1.3.3.11UniRule annotation)
    Alternative name(s):
    Coenzyme PQQ synthesis protein CUniRule annotation
    Pyrroloquinoline quinone biosynthesis protein CUniRule annotation
    Gene namesi
    Name:pqqCUniRule annotation
    Ordered Locus Names:Acry_0079
    OrganismiAcidiphilium cryptum (strain JF-5)
    Taxonomic identifieri349163 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeAcidiphilium
    ProteomesiUP000000245: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 246246Pyrroloquinoline-quinone synthasePRO_1000061666Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi349163.Acry_0079.

    Structurei

    3D structure databases

    ProteinModelPortaliA5FUM6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PqqC family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG5424.
    HOGENOMiHOG000217947.
    KOiK06137.
    OMAiRYHNLHR.
    OrthoDBiEOG6JTC7S.

    Family and domain databases

    Gene3Di1.20.910.10. 1 hit.
    HAMAPiMF_00654. PQQ_syn_PqqC.
    InterProiIPR016084. Haem_Oase-like_multi-hlx.
    IPR011845. PQQ_synth_PqqC.
    IPR004305. Thiaminase-2/PQQC.
    [Graphical view]
    PfamiPF03070. TENA_THI-4. 1 hit.
    [Graphical view]
    SUPFAMiSSF48613. SSF48613. 1 hit.
    TIGRFAMsiTIGR02111. PQQ_syn_pqqC. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5FUM6-1 [UniParc]FASTAAdd to Basket

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    MTVLMSPDEL EAALRAVGAA RYHNRHPFHQ LLHGGKLDKR QVQAWALNRY    50
    CYQAAIPIKD ATLIARTDDS ELRRIWRQRL VDHDGTQPGE GGIVRWLALA 100
    EGLGLDRDMV ISERRALPAT RFAVRAYVDF VRDRSLLEAV ASSLTEMFSP 150
    TIISERVSGM LANYDFITRE TLAYFNARLD QAPRDADFAL DYVKRHARTP 200
    EQQQAAIAAL TFKCDVLWAQ LDALHHAYVS PGLIPPGAFG HDGIWS 246
    Length:246
    Mass (Da):27,693
    Last modified:June 12, 2007 - v1
    Checksum:i06241FA6803AA75D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000697 Genomic DNA. Translation: ABQ29308.1.
    RefSeqiYP_001233227.1. NC_009484.1.

    Genome annotation databases

    EnsemblBacteriaiABQ29308; ABQ29308; Acry_0079.
    GeneIDi5162239.
    KEGGiacr:Acry_0079.
    PATRICi20645098. VBIAciCry6074_0556.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000697 Genomic DNA. Translation: ABQ29308.1 .
    RefSeqi YP_001233227.1. NC_009484.1.

    3D structure databases

    ProteinModelPortali A5FUM6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 349163.Acry_0079.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ29308 ; ABQ29308 ; Acry_0079 .
    GeneIDi 5162239.
    KEGGi acr:Acry_0079.
    PATRICi 20645098. VBIAciCry6074_0556.

    Phylogenomic databases

    eggNOGi COG5424.
    HOGENOMi HOG000217947.
    KOi K06137.
    OMAi RYHNLHR.
    OrthoDBi EOG6JTC7S.

    Enzyme and pathway databases

    UniPathwayi UPA00539 .
    BioCyci ACRY349163:GHET-81-MONOMER.

    Family and domain databases

    Gene3Di 1.20.910.10. 1 hit.
    HAMAPi MF_00654. PQQ_syn_PqqC.
    InterProi IPR016084. Haem_Oase-like_multi-hlx.
    IPR011845. PQQ_synth_PqqC.
    IPR004305. Thiaminase-2/PQQC.
    [Graphical view ]
    Pfami PF03070. TENA_THI-4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48613. SSF48613. 1 hit.
    TIGRFAMsi TIGR02111. PQQ_syn_pqqC. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JF-5.

    Entry informationi

    Entry nameiPQQC_ACICJ
    AccessioniPrimary (citable) accession number: A5FUM6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3