A5FTH3 (A5FTH3_ACICJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Acry_3292

Encoded on

Plasmid pACRY02 EMBL ABQ28905.1

Organism

Acidiphilium cryptum (strain JF-5) [Complete proteome] [HAMAP] EMBL ABQ28905.1

Taxonomic identifier

349163 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Acidiphilium

Protein attributes

Sequence length	1082 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome Plasmid EMBL ABQ28905.1
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5FTH3 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 620C8FDC46E2E0CD	FASTA	1,082	121,011
	10 20 30 40 50 60 MSTDTAYVEL HCTSHFSFLR GASSCDELFA QAAHLGLEAL AITDRNTLAG IVRAHVAAKA 70 80 90 100 110 120 NDMRLIVGCR LDLTDGTALL VYPTDRPAYA RLSRLLSLGK QRGGKAQCRL DWSDLVAYAE 130 140 150 160 170 180 GLIGVLVPGE ADDACVRNLR RLAQSFGDRA YLALTLRRRP NDALRLFELS NLAARAKVPT 190 200 210 220 230 240 VVTNDVLFHA RDRRILQDVV TCIRHGCTID DAGFRRERHA DRYLKPPAEM HRLFSRYPEA 250 260 270 280 290 300 LARTQEIADR CLFSLDELRY QYPDENVLPG LTTQEALTQL TWEGAAQRYP AGVPAEVVTI 310 320 330 340 350 360 LRHELRLIET LDYAPYFLTV NSIVRFARSQ GILCQGRGSA ANSAVCFVLG ITSIDPERND 370 380 390 400 410 420 LLFERFISEE RREPPDIDVD FEHERREIVM QWVFDTYGRD HAALCSTVIR YRTKGALRDV 430 440 450 460 470 480 GKALGLPEDL ITALNAQVWG WSEGGIEPKH AAELHLNLED RRLKLAIDLA RELIGTPRHL 490 500 510 520 530 540 SQHPGGFVLT RDRLDELVPI EPAAMDNRQI IEWDKDDIDA LKFMKVDCLA LGMLSCMKRG 550 560 570 580 590 600 FDLLAQHKGI ELDLATIPAE DPHTYAMIRR ADTLGTFQIE SRAQMVMLPR MKPRTFYDLV 610 620 630 640 650 660 IEVAIVRPGP IQGDMVHPYL RRREGKEAVV YPKPELEKVL GKTLGVPLFQ EQAMRVAIEC 670 680 690 700 710 720 AGFTATEADQ LRRSMATFKF TGGVSHFRDK LVSGMVANGY EQEFAERTFS QLEGFGSYGF 730 740 750 760 770 780 PESHAASFAL IAYASSWLKC HHPDVFCAAL LNAQPMGFYA PAQIVRDAKD HGVEIRPVCV 790 800 810 820 830 840 NASRWDCTLE PTHDESRLAV RLGLRMVKGV ANPHVAKMIA ARANHLFASV DDLWRRAGVP 850 860 870 880 890 900 TAALVQMAEA DAFLPSLKLA RRDALWAIKA LRDEALPLFA AVANRTEQPV SELQEPVFAL 910 920 930 940 950 960 KPLTGGGEVV EDYVHLGLSL RSHPVAYLRE DLRRERIVSC DQVMSTRDGK FLETAGIVLV 970 980 990 1000 1010 1020 RQRPGSARGV MFITIEDETG IANLVIWPNL YEKQRLIILS SGMIAVYGQI QREGEVVHLI 1030 1040 1050 1060 1070 1080 AHRLTDMSAA LASIGRRENV FPMPRGHCVG QDPRDTLGRA PGDIFVPDRH IDGIKVKSRD FR

References

[1]

"Complete sequence of plasmid2 pACRY02 of Acidiphilium cryptum JF-5." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Magnuson T., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JF-5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000690 Genomic DNA. Translation: ABQ28905.1.
RefSeq	YP_001220047.1. NC_009468.1.
3D structure databases
ProteinModelPortal	A5FTH3.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FTH3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5159250.
GenomeReviews	Gene locus Acry_3292 in contig CP000690_GR.
KEGG	acr:Acry_3292.
PATRIC	20644322. VBIAciCry6074_0174.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	ADYCANG.
ProtClustDB	CLSK881842.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5FTH3_ACICJ

Accession

Primary (citable) accession number: A5FTH3

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)