A5FPR2 (GCP_DEHSB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	DehaBAV1_1234

Organism

Dehalococcoides sp. (strain BAV1) [Complete proteome] [HAMAP]

Taxonomic identifier

216389 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Dehalococcoidetes › Dehalococcoides

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 326	326	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000087472

Sequences

	Sequence		Length	Mass (Da)
	A5FPR2 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 670DE1DF54C39A1B	FASTA	326	34,264
	10 20 30 40 50 60 MKILGIESSC DETAASVVED GVNILSNRIS SQIDIHSRYG GVVPEVASRQ HLLSILPVIK 70 80 90 100 110 120 DALEEARTGL DEISAIAITN GPGLAGSLIV GVNAAKAIAA ARRIPLVAVN HLHGHIYANW 130 140 150 160 170 180 LFGKIPEFPC LCLTVSGGHT DLVLMSGHGQ YQLLGRTRDD AAGEAFDKAA RILGLSYPGG 190 200 210 220 230 240 PAIDRASQDG QAVLDLPRSW IPGSHDFSFS GLKTALLRLV ESGEVCSVND AAASFQKAVV 250 260 270 280 290 300 DVLVTKTINC AQEYNVKQIL LAGGVAANNL LRKQLSEKSS LPVSIPPMGL CTDNAAVIAS 310 320 CGYFRFISGK QDGLDMDVLP ALSVTS

References

[1]

"Complete sequence of Dehalococcoides sp. BAV1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ritalahti K.M., Loeffler F., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BAV1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000688 Genomic DNA. Translation: ABQ17813.1.
RefSeq	YP_001214691.1. NC_009455.1.
3D structure databases
ProteinModelPortal	A5FPR2.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FPR2.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5132095.
GenomeReviews	Gene locus DehaBAV1_1234 in contig CP000688_GR.
KEGG	deb:DehaBAV1_1234.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	DSP216389:DEHABAV1_1234-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_DEHSB

Accession

Primary (citable) accession number: A5FPR2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	June 12, 2007
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program