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A5FP84

- PYRF_DEHMB

UniProt

A5FP84 - PYRF_DEHMB

Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Dehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei89 – 891Proton donorUniRule annotation

    GO - Molecular functioni

    1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    BioCyciDSP216389:GH6D-12-MONOMER.
    UniPathwayiUPA00070; UER00120.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Orotidine 5'-phosphate decarboxylaseUniRule annotation (EC:4.1.1.23UniRule annotation)
    Alternative name(s):
    OMP decarboxylaseUniRule annotation
    Short name:
    OMPDCaseUniRule annotation
    Short name:
    OMPdecaseUniRule annotation
    Gene namesi
    Name:pyrFUniRule annotation
    Ordered Locus Names:DehaBAV1_0012
    OrganismiDehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)
    Taxonomic identifieri216389 [NCBI]
    Taxonomic lineageiBacteriaChloroflexiDehalococcoidiaDehalococcoidalesDehalococcoidaceaeDehalococcoides
    ProteomesiUP000002607: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 270270Orotidine 5'-phosphate decarboxylasePRO_1000085574Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi216389.DehaBAV1_0012.

    Structurei

    3D structure databases

    ProteinModelPortaliA5FP84.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the OMP decarboxylase family. Type 2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0284.
    HOGENOMiHOG000245747.
    KOiK01591.
    OMAiCRTSNAG.
    OrthoDBiEOG6DZF33.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_01215. OMPdecase_type2.
    InterProiIPR013785. Aldolase_TIM.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00215. OMPdecase. 1 hit.
    [Graphical view]
    SMARTiSM00934. OMPdecase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5FP84-1 [UniParc]FASTAAdd to Basket

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    MKFLEKLKQA GNRNKSLLCV GLDPDPKLMP VGMSALEFNR EIIEATAPFV    50
    CGYKINLAFY EALGKQGWEI LSETCEFIPR ELITIADAKR GDIGNTSKAY 100
    ARAILDELDC DGVTVSPYLG YDSLEPFIEY QDKGIFILCL TSNQGSTDFQ 150
    MLKTEYLGQK RFLYEVVADK ASLWNRYENI GLVVGATQQE ELKKLRLIYP 200
    KLPFLIPGIG AQGGDLKATI ENGTNPNGEL AIICASRGIL YARSGSEFAQ 250
    GAAEAAEQMR DAINHYRKRF 270
    Length:270
    Mass (Da):30,014
    Last modified:June 12, 2007 - v1
    Checksum:i860F3DF039F01284
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000688 Genomic DNA. Translation: ABQ16604.1.
    RefSeqiYP_001213482.1. NC_009455.1.

    Genome annotation databases

    EnsemblBacteriaiABQ16604; ABQ16604; DehaBAV1_0012.
    GeneIDi5131616.
    KEGGideb:DehaBAV1_0012.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000688 Genomic DNA. Translation: ABQ16604.1 .
    RefSeqi YP_001213482.1. NC_009455.1.

    3D structure databases

    ProteinModelPortali A5FP84.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 216389.DehaBAV1_0012.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ16604 ; ABQ16604 ; DehaBAV1_0012 .
    GeneIDi 5131616.
    KEGGi deb:DehaBAV1_0012.

    Phylogenomic databases

    eggNOGi COG0284.
    HOGENOMi HOG000245747.
    KOi K01591.
    OMAi CRTSNAG.
    OrthoDBi EOG6DZF33.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00120 .
    BioCyci DSP216389:GH6D-12-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_01215. OMPdecase_type2.
    InterProi IPR013785. Aldolase_TIM.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00215. OMPdecase. 1 hit.
    [Graphical view ]
    SMARTi SM00934. OMPdecase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1.

    Entry informationi

    Entry nameiPYRF_DEHMB
    AccessioniPrimary (citable) accession number: A5FP84
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3