A5FP28 (A5FP28_FLAJ1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	Fjoh_0005

Organism

Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]

Taxonomic identifier

376686 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377 RuleBase RU000577
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 RuleBase RU000577 DNA-binding HAMAP MF_00377 RuleBase RU000577 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	180 – 187	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	A5FP28 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 4E6D59E6B85248A3	FASTA	475	54,506
	10 20 30 40 50 60 MTKTAQSVWE NCLSFIKDNI QDQAYKTWFE PIKSVELTDN ALYIQVPSKF FYEWLEEHYV 70 80 90 100 110 120 KLLKVALTKE LGKNAKLLYK IKMENTYGNK QPFTEQLPSS NRVPMKPQEV DAPFKNLNPE 130 140 150 160 170 180 LKNPFVIPGI RNLKIESQLN PNYSFDNFLE GDSNRLARSA GMAVANKPGG TSFNPLLIFG 190 200 210 220 230 240 GVGLGKTHLA HAIGVEVKDK YPEKTVLYIS AEIFTQQYID SVKKNNRNDF IHFYQLIDVL 250 260 270 280 290 300 IIDDVQFLSG KSGTQDVFFH IFNYLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA 310 320 330 340 350 360 ELHQPDYETR ISILKNILYR DGVDMPEDIL EYVARNIKSN VRELEGAIIS LIAQSSFNKK 370 380 390 400 410 420 EVTIELAKSV VEKFVKNVKR EISIDYIQKI VSDYFQLDIE TLQSKTRKRH VVQARQLAMF 430 440 450 460 470 FAKKFTKASL ANIGSQIGDR DHATVLHACK TVDNLVSTDK QFKKFVEDIN KKLTL

References

[1]

"Complete sequence of Flavobacterium johnsoniae UW101." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000685 Genomic DNA. Translation: ABQ03043.1.
RefSeq	YP_001192362.1. NC_009441.1.
3D structure databases
ProteinModelPortal	A5FP28.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FP28.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5091161.
GenomeReviews	Gene locus Fjoh_0005 in contig CP000685_GR.
KEGG	fjo:Fjoh_0005.
PATRIC	21894203. VBIFlaJoh53613_0005.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0593.
HOGENOM	HBG695666.
OMA	CHTLNAL.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5FP28_FLAJ1

Accession

Primary (citable) accession number: A5FP28

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)