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A5FND6 (SYR_FLAJ1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Fjoh_0251
OrganismFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]
Taxonomic identifier376686 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium

Protein attributes

Sequence length592 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 592592Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000076215

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A5FND6 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: ECCEE9EBDB971A24

FASTA59267,140
        10         20         30         40         50         60 
MSLSQILTPS IQKAIQVLFD VSVDKIEFQT TRKEFEGDIT MVIFPLLKVI KSNPAELGNK 

        70         80         90        100        110        120 
IGTYLVENVS EVARFNVVSG FLNIVISDSY YVDFFNGIKD QKQFGFLSPN PEEKAVMVEY 

       130        140        150        160        170        180 
SSPNTNKPLH LGHVRNNLLG YSVAEILKAS GKKVYKTQII NDRGIHICKS MLAWEKFGNG 

       190        200        210        220        230        240 
ETPESSDLKG DKLVGKYYVE FDKAYKTEIN QLIETGKTEE EAKKQAPIII EAQEMLKKWE 

       250        260        270        280        290        300 
AGDEQVIALW KKMNQWVYDG FATTYTNLGV NFDKYYYESN TYLLGKDVVQ VGLDKGVFEK 

       310        320        330        340        350        360 
DPDGSVWIDL TDEGLDRKIV LRSDGTAVYM TQDIGTAIQR VKDMPDVGGM VYTVGNEQDY 

       370        380        390        400        410        420 
HFKVLFLILK KLGFDWASSL YHLSYGMVDL PSGKMKSREG TVVDADDLMQ DMTDTAKQIA 

       430        440        450        460        470        480 
EDLGKLDSYS ADEKAKLYKT IGLGALKYYI LKVDPKKRIL FNPEESVDFA GNTGPFIQYT 

       490        500        510        520        530        540 
YARIQSIIRK ADFDFSNKIE IEELHEKEKE LVKQIELFPE VIQNAAQNHS PALIANYTYD 

       550        560        570        580        590 
LVKEYNSFYQ SVHILGEADL TKKIFRVQLS QKVAEVIKSA FSLLGIEVPE RM 

« Hide

References

[1]"Complete sequence of Flavobacterium johnsoniae UW101."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000685 Genomic DNA. Translation: ABQ03287.1.
RefSeqYP_001192606.1. NC_009441.1.

3D structure databases

ProteinModelPortalA5FND6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING376686.Fjoh_0251.

Proteomic databases

PRIDEA5FND6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ03287; ABQ03287; Fjoh_0251.
GeneID5094145.
KEGGfjo:Fjoh_0251.
PATRIC21894739. VBIFlaJoh53613_0263.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247211.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycFJOH376686:GIXN-262-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_FLAJ1
AccessionPrimary (citable) accession number: A5FND6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: April 16, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries