A5FME9 (A5FME9_FLAJ1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thymidine kinase HAMAP MF_00124
EC=2.7.1.21 HAMAP MF_00124

Gene names

Name:	tdk HAMAP MF_00124
Ordered Locus Names:	Fjoh_0586

Organism

Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]

Taxonomic identifier

376686 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP MF_00124 SAAS SAAS020634
Subunit structure	Homotetramer By similarity. HAMAP MF_00124
Subcellular location	Cytoplasm By similarity HAMAP MF_00124.
Sequence similarities	Belongs to the thymidine kinase family. HAMAP MF_00124

Ontologies

Keywords
Biological process	DNA synthesis HAMAP MF_00124 SAAS SAAS020634
Cellular component	Cytoplasm HAMAP MF_00124
Ligand	ATP-binding HAMAP MF_00124 SAAS SAAS020634 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00124 SAAS SAAS020634 EMBL ABQ03621.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP thymidine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	21 – 28	8	ATP By similarity HAMAP MF_00124
	Nucleotide binding	93 – 96	4	ATP By similarity HAMAP MF_00124
Sites
	Active site	94	1	Proton acceptor By similarity HAMAP MF_00124

Sequences

	Sequence		Length	Mass (Da)
	A5FME9 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 7751DD4FCD837FEB	FASTA	194	21,788
	10 20 30 40 50 60 MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAQF AKQRVEIFKP AIDTRYHDEM 70 80 90 100 110 120 VVSHDANEIR STPVPAAANI SILAQGCDVV GIDEAQFFDD EIVTVCNDLA NRGVRVIVAG 130 140 150 160 170 180 LDMDFKGNPF GPMPALMATA EYVTKVHAVC TRTGNLANYS FRKTDNDKLV MLGETEEYEP 190 LSRAAYFNAM KKNQ

References

[1]

"Complete sequence of Flavobacterium johnsoniae UW101." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000685 Genomic DNA. Translation: ABQ03621.1.
RefSeq	YP_001192940.1. NC_009441.1.
3D structure databases
ProteinModelPortal	A5FME9.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FME9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5090892.
GenomeReviews	Gene locus Fjoh_0586 in contig CP000685_GR.
KEGG	fjo:Fjoh_0586.
PATRIC	21895435. VBIFlaJoh53613_0604.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1435.
HOGENOM	HBG522108.
OMA	EPRCRHH.
ProtClustDB	PRK04296.
Family and domain databases
HAMAP	MF_00124. Thymidine_kinase. [Tree]
InterPro	IPR001267. Thymidine_kinase. IPR020634. Thymidine_kinase_subgr. [Graphical view]
KO	K00857.
PANTHER	PTHR11441. TK_cell. 1 hit.
Pfam	PF00265. TK. 1 hit. [Graphical view]
PIRSF	PIRSF035805. TK_cell. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5FME9_FLAJ1

Accession

Primary (citable) accession number: A5FME9

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)