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A5FLE0 (A5FLE0_FLAJ1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Fjoh_0939
OrganismFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]
Taxonomic identifier376686 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1881Iron By similarity HAMAP MF_00323
Metal binding2911Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A5FLE0 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 4A5304A6AFABA68D

FASTA33738,589
        10         20         30         40         50         60 
MKGVLLVNLG SPDSPTTKDV KPYLDEFLMD KYVIDVPYLL RALLVRGIIL RKRPEESAHA 

        70         80         90        100        110        120 
YAKIWWEEGS PLVVLSERMQ KKVQPLVNVP VSLAMRYGSM TIEKGLQELS DKGVTDVMLF 

       130        140        150        160        170        180 
PLYPQYAMAS TLTILVKAEE IRKKKFPHMK FTDVPAFYNK PDYIKNLADS IQKHLVGFDY 

       190        200        210        220        230        240 
DHLLFSYHGI PERHIRKTDV TKSHCKIDGS CCNTPSPAHE FCYRHQCYET TRQVVKLLGL 

       250        260        270        280        290        300 
PEDKYSLTFQ SRLAGDKWLE PYTDVEIDNM PAKGIKKLAV VTPAFVSDCL ETLEEIAMRA 

       310        320        330 
KEDFEANGGE EFLAIPCLND DDEWCQTVSN WINDWAK

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References

[1]"Complete sequence of Flavobacterium johnsoniae UW101."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000685 Genomic DNA. Translation: ABQ03973.1.
RefSeqYP_001193292.1. NC_009441.1.

3D structure databases

ProteinModelPortalA5FLE0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5FLE0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5091353.
GenomeReviewsGene locus Fjoh_0939 in contig CP000685_GR.
KEGGfjo:Fjoh_0939.
PATRIC21896163. VBIFlaJoh53613_0966.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMATIEEIGM.
ProtClustDBCLSK851820.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5FLE0_FLAJ1
AccessionPrimary (citable) accession number: A5FLE0
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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