A5FK15 (A5FK15_FLAJ1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Candidate lipid-A-disaccharide synthase; Glycosyltransferase family 19 EMBL ABQ04459.1
EC=2.4.1.182 EMBL ABQ04459.1

Gene names

Ordered Locus Names:

Fjoh_1427

Organism

Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]

Taxonomic identifier

376686 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABQ04459.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5FK15 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 38DD074E4B5CA43E	FASTA	371	42,497
	10 20 30 40 50 60 MKYYIIAGEA SGDLHGSNLM KALYEEDPQA EIRFWGGDLM QKAGGTLVKH YRDLAFMGFV 70 80 90 100 110 120 EVLFNLKTIL NNIKFCKKDI SEFKPDVLIF IDYPGFNMRI AKWAKELNYR THYYISPQIW 130 140 150 160 170 180 AWKENRINAI KQDVDRMFVI LPFEKGFYED KHHFPVDFVG HPLIDAIQNQ PAFNEAAFRE 190 200 210 220 230 240 ENKLGEKPII AVLPGSRKQE ITKMLSVMLS VVDDFQDYEF VIAGAPSQDY EFYQQFIKNK 250 260 270 280 290 300 NIAFVSNKTY DLLRSSTAAL VTSGTATLET ALFKVPEVVC YKGSAISYQI AKRIITLKYI 310 320 330 340 350 360 SLVNLIMDQE VVTELIQGEC NTKRIKEELN KLLEPSHREK LLKNYDILEQ KLGGVGASKK 370 TAKLIVADLK S

References

[1]

"Complete sequence of Flavobacterium johnsoniae UW101." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000685 Genomic DNA. Translation: ABQ04459.1.
RefSeq	YP_001193778.1. NC_009441.1.
3D structure databases
ProteinModelPortal	A5FK15.
ModBase	Search...
Protein-protein interaction databases
STRING	A5FK15.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5092433.
GenomeReviews	Gene locus Fjoh_1427 in contig CP000685_GR.
KEGG	fjo:Fjoh_1427.
PATRIC	21897185. VBIFlaJoh53613_1468.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	AEFAFIC.
ProtClustDB	CLSK823744.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5FK15_FLAJ1

Accession

Primary (citable) accession number: A5FK15

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)