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A5FIY1 (A5FIY1_FLAJ1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoylalanine--D-glutamate ligase HAMAP MF_00639 RuleBase RU003664
EC=6.3.2.9 HAMAP MF_00639 RuleBase RU003664
Alternative name(s):
D-glutamic acid-adding enzyme HAMAP MF_00639
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase HAMAP MF_00639
Gene names
Name:murD HAMAP MF_00639
Ordered Locus Names:Fjoh_1808
OrganismFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]
Taxonomic identifier376686 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) By similarity. HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762

Subcellular location

Cytoplasm By similarity HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762.

Sequence similarities

Belongs to the MurCDEF family. HAMAP MF_00639 RuleBase RU003630

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding108 – 1147ATP By similarity HAMAP MF_00639

Sequences

Sequence LengthMass (Da)Tools
A5FIY1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 0FEAD0AD0425402E

FASTA44349,401
        10         20         30         40         50         60 
MRLVVLGGGE SGVGTAILGK KKGYDVFVSD FGKIKESYKE VLIINKIDWE EEQHTEDLIL 

        70         80         90        100        110        120 
NADVVMKSPG IPDKSPIIKK LVAAGVKVIS EIEFAKPFTE ALTIGITGSN GKTTTTMLTH 

       130        140        150        160        170        180 
HLLKSAGLNV GLGGNIGKSF AWQVAENKYD AYVLELSSFQ LDGIIDYRPD IAIITNISPD 

       190        200        210        220        230        240 
HLDRYEYKYE NYINSKFRIT MNQTESDYLI YDADDEASTE WLKNNKTKAK LIPFSLTKTF 

       250        260        270        280        290        300 
DEGASINNNK MEIKINQEEF TMETEHIALE GKHNMKNAMA ASSVAKLMQI RNATIRESLS 

       310        320        330        340        350        360 
NFQGVEHRLE KVLKIQNVQY INDSKATNVN ATFFALDSMN VPTVWIVGGV DKGNDYNELM 

       370        380        390        400        410        420 
SLVREKVKAI ICLGIDNRKI IDAFGAVVDI MVEVNNMNDA VKTAQRLTEK GDAVLLSPAC 

       430        440 
ASFDLFENYE DRGKQFKQAV HNL

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References

[1]"Complete sequence of Flavobacterium johnsoniae UW101."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000685 Genomic DNA. Translation: ABQ04840.1.
RefSeqYP_001194159.1. NC_009441.1.

3D structure databases

ProteinModelPortalA5FIY1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5FIY1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5091875.
GenomeReviewsGene locus Fjoh_1808 in contig CP000685_GR.
KEGGfjo:Fjoh_1808.
PATRIC21897975. VBIFlaJoh53613_1857.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0771.
HOGENOMHBG750024.
OMAACASWDM.
ProtClustDBCLSK823532.

Family and domain databases

HAMAPMF_00639. MurD.
[Tree]
InterProIPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR016040. NAD(P)-bd_dom.
IPR005762. UDP-N-AcMur-Glu_ligase.
[Graphical view]
Gene3DG3DSA:3.90.190.20. Mur_ligase_C. 1 hit.
G3DSA:3.40.1190.10. Mur_ligase_cen. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK01925.
PANTHERPTHR23135:SF2. PTHR23135:SF2. 1 hit.
PfamPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. Mur_ligase_C. 1 hit.
SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMsTIGR01087. MurD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5FIY1_FLAJ1
AccessionPrimary (citable) accession number: A5FIY1
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info