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Protein

Proline iminopeptidase

Gene

fpaP

Organism
Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Releases the N-terminal proline from various substrates.By similarity

Catalytic activityi

Release of N-terminal proline from a peptide.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei103 – 1031NucleophileBy similarity
Active sitei243 – 2431By similarity
Active sitei270 – 2701Proton donorBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Aminopeptidase, Hydrolase, Protease

Enzyme and pathway databases

BioCyciFJOH376686:GIXN-2034-MONOMER.

Protein family/group databases

ESTHERiflaj1-pip. Proline_iminopeptidase.

Names & Taxonomyi

Protein namesi
Recommended name:
Proline iminopeptidaseBy similarity (EC:3.4.11.5)
Short name:
PIPBy similarity
Alternative name(s):
Prolyl aminopeptidaseBy similarity
Short name:
PAPBy similarity
Gene namesi
Name:fpaP
Ordered Locus Names:Fjoh_1984
OrganismiFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae)
Taxonomic identifieri376686 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
Proteomesi
  • UP000006694 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 297297Proline iminopeptidasePRO_0000406319Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi376686.Fjoh_1984.

Structurei

3D structure databases

ProteinModelPortaliA5FIF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S33 family.Sequence analysis

Phylogenomic databases

eggNOGiENOG4107T66. Bacteria.
ENOG410ZVIC. LUCA.
HOGENOMiHOG000026004.
KOiK01259.
OrthoDBiPOG091H04PE.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR002410. Peptidase_S33.
IPR005945. Pro_imino_pep.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005539. Pept_S33_TRI_F1. 1 hit.
PRINTSiPR00793. PROAMNOPTASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
TIGRFAMsiTIGR01250. pro_imino_pep_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A5FIF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPIKTPVGE FKVWIKRFGT NPKIKVLLLH GGPAMTHEYM ECFETFFQRE
60 70 80 90 100
GFEFYEYDQL GSYYSDQPKD SSLWTIDRFV DEVEQVRKAI NADKDNFYVL
110 120 130 140 150
GNSWGGILAM EYALKYQQNM KGLLVSNMMA SAPEYGKYAD EVLAKQMKPE
160 170 180 190 200
ILKEIRDLEA KKDFENPRYM ELLLPNFYKE HLCRLNEWPD GLNRASKHVN
210 220 230 240 250
GEIYTLMQGP SEFGISGRLA KWDIKNRLHE ITIPTLMIGA KYDTMDPKAM
260 270 280 290
EEQSKLVKKG RYLYCPNGSH LAMWDDQKVF MNGVIQFIND VNDEKVN
Length:297
Mass (Da):34,609
Last modified:April 5, 2011 - v2
Checksum:i0E6199B8B9A7879C
GO

Sequence cautioni

The sequence ABQ05016 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000685 Genomic DNA. Translation: ABQ05016.1. Different initiation.
RefSeqiWP_012024056.1. NC_009441.1.

Genome annotation databases

EnsemblBacteriaiABQ05016; ABQ05016; Fjoh_1984.
KEGGifjo:Fjoh_1984.
PATRICi21898359. VBIFlaJoh53613_2037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000685 Genomic DNA. Translation: ABQ05016.1. Different initiation.
RefSeqiWP_012024056.1. NC_009441.1.

3D structure databases

ProteinModelPortaliA5FIF5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi376686.Fjoh_1984.

Protein family/group databases

ESTHERiflaj1-pip. Proline_iminopeptidase.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ05016; ABQ05016; Fjoh_1984.
KEGGifjo:Fjoh_1984.
PATRICi21898359. VBIFlaJoh53613_2037.

Phylogenomic databases

eggNOGiENOG4107T66. Bacteria.
ENOG410ZVIC. LUCA.
HOGENOMiHOG000026004.
KOiK01259.
OrthoDBiPOG091H04PE.

Enzyme and pathway databases

BioCyciFJOH376686:GIXN-2034-MONOMER.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR002410. Peptidase_S33.
IPR005945. Pro_imino_pep.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005539. Pept_S33_TRI_F1. 1 hit.
PRINTSiPR00793. PROAMNOPTASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
TIGRFAMsiTIGR01250. pro_imino_pep_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPIP_FLAJ1
AccessioniPrimary (citable) accession number: A5FIF5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.