ID   RLMF_FLAJ1              Reviewed;         316 AA.
AC   A5FHX5;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   16-JUN-2009, entry version 16.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase F;
DE            EC=2.1.1.48;
DE   AltName: Full=23S rRNA mA1618 methyltransferase;
DE   AltName: Full=rRNA adenine N-6-methyltransferase;
GN   Name=rlmF; OrderedLocusNames=Fjoh_2174;
OS   Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101)
OS   (Cytophaga johnsonae).
OC   Bacteria; Bacteroidetes; Flavobacteria; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=376686;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.,
RA   Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Xie G., McBride M., Richardson P.;
RT   "Complete sequence of Flavobacterium johnsoniae UW101.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the adenine in position 1618 of
CC       23S rRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-
CC       homocysteine + rRNA containing N(6)-methyladenine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       METT10D/rlmF family.
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DR   EMBL; CP000685; ABQ05202.1; -; Genomic_DNA.
DR   RefSeq; YP_001194521.1; -.
DR   GeneID; 5092793; -.
DR   GenomeReviews; CP000685_GR; Fjoh_2174.
DR   KEGG; fjo:Fjoh_2174; -.
DR   OMA; A5FHX5; LNFGGQN.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008988; F:rRNA (adenine-N6-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0000154; P:rRNA modification; IEA:InterPro.
DR   HAMAP; MF_01848; -; 1.
DR   InterPro; IPR016909; S-AdoMet-dep_MeTrfase_YbiN_prd.
DR   InterPro; IPR010286; SAM-Mtase_prd.
DR   PANTHER; PTHR13393; DUF890; 1.
DR   Pfam; PF05971; Methyltransf_10; 1.
DR   PIRSF; PIRSF029038; Mtase_YbiN_prd; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    316       Ribosomal RNA large subunit
FT                                methyltransferase F.
FT                                /FTId=PRO_0000349916.
SQ   SEQUENCE   316 AA;  35867 MW;  60D45F1506CDF5C8 CRC64;
     MKAENNSQKD NLHPRNLHRS RYDFELLISN CPELKAFISI NKHGIETVDF SNPLAVKTLN
     KALLQTYYDI QNWDIPKNYL CPPIPGRADY IHYLADLLAE TNNGKIPEGN SVMGLDIGTG
     ANLIYPILGN SIYNWSFVAT DIYKTSIENA SKIIEANPRL IDAVSLQQQT EPRFIFKNII
     IPEDRFTFTM CNPPFHASAE EANKSTSRKV SNLNPKEKKN TNPVLNFGGQ NAELWCNGGE
     IGFITQMIYE SVKYASQVLW FTTLVSKKEN LSSIYKTLKK VNAVSVKTIE MSQGQKNSRI
     VAWSFLNNTE QKSWKF
//