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Protein

DNA topoisomerase

Gene

Fjoh_2289

Organism
Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase, TopoisomeraseSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Enzyme and pathway databases

BioCyciFJOH376686:GIXN-2346-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA topoisomeraseSAAS annotation (EC:5.99.1.2SAAS annotation)
Gene namesi
Ordered Locus Names:Fjoh_2289Imported
OrganismiFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae)Imported
Taxonomic identifieri376686 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
Proteomesi
  • UP000006694 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi376686.Fjoh_2289.

Structurei

3D structure databases

ProteinModelPortaliA5FHK0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 134134ToprimInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the type IA topoisomerase family.SAAS annotation
Contains Toprim domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG4107QWF. Bacteria.
COG0550. LUCA.
HOGENOMiHOG000086847.
KOiK03169.
OMAiRKVGYQG.
OrthoDBiEOG60CWM6.

Family and domain databases

Gene3Di1.10.460.10. 2 hits.
2.70.20.10. 2 hits.
3.40.50.140. 1 hit.
InterProiIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR005738. TopoIII.
IPR006171. Toprim_domain.
[Graphical view]
PANTHERiPTHR11390. PTHR11390. 3 hits.
PfamiPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSiPR00417. PRTPISMRASEI.
SMARTiSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF56712. SSF56712. 1 hit.
TIGRFAMsiTIGR01056. topB. 1 hit.
PROSITEiPS50880. TOPRIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5FHK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVCIAEKPS VAREIASVLG ANTKHDGYYE GNGYAVTYTF GHLCTLKEPN
60 70 80 90 100
DYKPHWKSWD LNNLPMLPEK FETKVVQNSG IQKQFKIIKT LFDKAELVIN
110 120 130 140 150
CGDAGQEGEL IQRWVMNEAH YKGEIKRLWI SSLTTEAIKE GFDNLKPSEN
160 170 180 190 200
YDNLFYAGFS RAIGDWLLGM NATRLYTVKH GGYKQVLSIG RVQTPTLAMV
210 220 230 240 250
VDRFKEIENF KPQPYWELQT LYRETLFSYE EGRFLKKEDG EILAEKVKES
260 270 280 290 300
DFEIVSVDKK NGNEYAPKLF DLTGLQVYCN QKFGFSAEET LKIAQTLYEQ
310 320 330 340 350
KAITYPRVDT TFLPGDIYPK VPGILQKLTN YSHLTEPLLG KKIKKSPKVF
360 370 380 390 400
NDKKVTDHHA IIPTGIEINL PYNQQQVYDI IVKRFLAVFY DDCLVANTTV
410 420 430 440 450
IGKAADVTFK ATGKEILKKG FRVVFEDPNA KEKEPDLLPS FVVGEKGPHE
460 470 480 490 500
PSFLQKETKP PNHFTEATLL RAMETAGKQV DDEDLRELMK ENGIGRPSTR
510 520 530 540 550
ANIIETLFKR QYIVRNKKQV LPTTTGIQLI DTIQNELIKS AELTGSWEKQ
560 570 580 590 600
LKDIEKGTFT AAAFIRNMKR MVEALVTEVR SETRHANISH AATIQKPAVK
610 620 630 640 650
AEKKKAAGIL AETCPKCQKG NFIKGKSAFG CSEYKSGCDF VLPYGFHDKK
660 670 680 690 700
ITESQYLRLV QKGSTVNIKG FKTDAGTVEG LIRFEENYKL KLEPKKTYIK
710 720 730 740 750
KTTKETASDS LSCPKCKKGN ILKGKTAYGC SEYKSGCDFK VTFDEVRAKL
760
QDQKPTKELV YSILEGSV
Length:768
Mass (Da):86,949
Last modified:June 12, 2007 - v1
Checksum:i8CB7AD9C35F07CBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000685 Genomic DNA. Translation: ABQ05316.1.
RefSeqiWP_012024355.1. NC_009441.1.

Genome annotation databases

EnsemblBacteriaiABQ05316; ABQ05316; Fjoh_2289.
KEGGifjo:Fjoh_2289.
PATRICi21899009. VBIFlaJoh53613_2356.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000685 Genomic DNA. Translation: ABQ05316.1.
RefSeqiWP_012024355.1. NC_009441.1.

3D structure databases

ProteinModelPortaliA5FHK0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi376686.Fjoh_2289.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ05316; ABQ05316; Fjoh_2289.
KEGGifjo:Fjoh_2289.
PATRICi21899009. VBIFlaJoh53613_2356.

Phylogenomic databases

eggNOGiENOG4107QWF. Bacteria.
COG0550. LUCA.
HOGENOMiHOG000086847.
KOiK03169.
OMAiRKVGYQG.
OrthoDBiEOG60CWM6.

Enzyme and pathway databases

BioCyciFJOH376686:GIXN-2346-MONOMER.

Family and domain databases

Gene3Di1.10.460.10. 2 hits.
2.70.20.10. 2 hits.
3.40.50.140. 1 hit.
InterProiIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR005738. TopoIII.
IPR006171. Toprim_domain.
[Graphical view]
PANTHERiPTHR11390. PTHR11390. 3 hits.
PfamiPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSiPR00417. PRTPISMRASEI.
SMARTiSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF56712. SSF56712. 1 hit.
TIGRFAMsiTIGR01056. topB. 1 hit.
PROSITEiPS50880. TOPRIM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel features of the polysaccharide-digesting gliding bacterium Flavobacterium johnsoniae as revealed by genome sequence analysis."
    McBride M.J., Xie G., Martens E.C., Lapidus A., Henrissat B., Rhodes R.G., Goltsman E., Wang W., Xu J., Hunnicutt D.W., Staroscik A.M., Hoover T.R., Cheng Y.Q., Stein J.L.
    Appl. Environ. Microbiol. 75:6864-6875(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17061 / DSM 2064 / UW101Imported.

Entry informationi

Entry nameiA5FHK0_FLAJ1
AccessioniPrimary (citable) accession number: A5FHK0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: May 11, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.