A5FGX2 (MQO_FLAJ1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	Fjoh_2529

Organism

Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]

Taxonomic identifier

376686 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	497 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 497	497	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000204199

Sequences

	Sequence		Length	Mass (Da)
	A5FGX2 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 1232893BDFB371EF	FASTA	497	55,293
	10 20 30 40 50 60 MPDNTIRSNS EVVLIGAGIM SATLGLILKE LQPDIKIEIY ERLDVAAAES SDAWNNAGTG 70 80 90 100 110 120 HSAFCELNYT PEKADGSIDP KKAISIAESF EISRQFWSYL VQQNKVPSPE NFIKSVPHMS 130 140 150 160 170 180 FVWGDKNVEY LRKRFEALQS NPIFADMTFS TDFNQLKEWM PLVMEGREAD EKLAATHMEI 190 200 210 220 230 240 GTDVNFGALT RSMFNYLEKL DGVTLYFNHE VKKLKQREDK SWRIKITDLS TGQKRKAYTK 250 260 270 280 290 300 FVFIGAGGGS LPLLEKADVP EGHGYGGFPV SGQWLKCTNP EVIAKHQAKV YGKASVGAPP 310 320 330 340 350 360 MSVPHIDTRV IDGEKALLFG PFAGFSTRFL KNGSYLDLPL SIKANNLIPM LSAGFHNIPL 370 380 390 400 410 420 TKYLIEQVRQ SPKDRMKALR EYLPTARSKD WKLEKAGQRV QVIKKGKDGG GVLEFGTEVI 430 440 450 460 470 480 NTHDGTLAVL LGASPGASTA VAIMVDLISR CFTNQIKTPE WEAKMKEMIP SYGKTLNDKP 490 ELLAEMRKHT AEVLKIK

References

[1]

"Complete sequence of Flavobacterium johnsoniae UW101." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000685 Genomic DNA. Translation: ABQ05556.1.
RefSeq	YP_001194875.1. NC_009441.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5FGX2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5091983.
GenomeReviews	Gene locus Fjoh_2529 in contig CP000685_GR.
KEGG	fjo:Fjoh_2529.
PATRIC	21899497. VBIFlaJoh53613_2600.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	KKWVPLM.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	FJOH376686:FJOH_2529-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_FLAJ1

Accession

Primary (citable) accession number: A5FGX2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 12, 2007
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program