ID   A5FFY2_FLAJ1            Unreviewed;       636 AA.
AC   A5FFY2;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE            EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN   OrderedLocusNames=Fjoh_2859 {ECO:0000313|EMBL:ABQ05880.1};
OS   Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC
OS   14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=376686 {ECO:0000313|EMBL:ABQ05880.1, ECO:0000313|Proteomes:UP000006694};
RN   [1] {ECO:0000313|EMBL:ABQ05880.1, ECO:0000313|Proteomes:UP000006694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 /
RC   UW101 {ECO:0000313|Proteomes:UP000006694};
RX   PubMed=19717629; DOI=10.1128/AEM.01495-09;
RA   McBride M.J., Xie G., Martens E.C., Lapidus A., Henrissat B., Rhodes R.G.,
RA   Goltsman E., Wang W., Xu J., Hunnicutt D.W., Staroscik A.M., Hoover T.R.,
RA   Cheng Y.Q., Stein J.L.;
RT   "Novel features of the polysaccharide-digesting gliding bacterium
RT   Flavobacterium johnsoniae as revealed by genome sequence analysis.";
RL   Appl. Environ. Microbiol. 75:6864-6875(2009).
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DR   EMBL; CP000685; ABQ05880.1; -; Genomic_DNA.
DR   RefSeq; WP_012024918.1; NC_009441.1.
DR   AlphaFoldDB; A5FFY2; -.
DR   STRING; 376686.Fjoh_2859; -.
DR   KEGG; fjo:Fjoh_2859; -.
DR   eggNOG; COG0365; Bacteria.
DR   HOGENOM; CLU_000022_3_6_10; -.
DR   OrthoDB; 9778383at2; -.
DR   Proteomes; UP000006694; Chromosome.
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR   CDD; cd05966; ACS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR011904; Ac_CoA_lig.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR   PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR   PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABQ05880.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          12..68
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          70..462
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          519..598
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   636 AA;  71886 MW;  A55EEB9358F00120 CRC64;
     MSYYKIENLE QYFKHYNKSI REPRKFWGKI AEENFTWYQQ WEKVVDFNMA DAEVKWFTEA
     KVNITKNCID RHLSKRGDKT AIIFEPNEPS EEALHITYNE LYERVSKMAN VLREQGIRKG
     DRVCIYLPMI PELAVAVLAC ARIGAIHSVV FAGFSASAVS ARINDCECKM VITSDGGYRG
     NKTIDLKGIV DEALDTCPSV SKVLVVKRTK TEIAMKEGRD IWLQPLLDAA LDNSVAEIMD
     AEDPLFILYT SGSTGKPKGM VHTTAGYMVY TAYTFKNVFS HEENDIFWCT ADIGWITGHS
     YILYGPLLNG GTTVIFEGVP SYPDFSRFWD IIEKHKITQF YTAPTAIRSL AKESLDYIQK
     YPLKSLKVIG SVGEPINEEA WHWFNDHVGD KRCPVVDTWW QTETGGIMIS PIAFVTPTKP
     TYATLPLPGI QPVLMDEKRN EIEGNQVVGS LCIKFPWPGI ARTIWNNHDR YKETYFSAFP
     GKYFTGDGAL RDEVGYYRIT GRVDDVVIVS GHNLGTAPIE DAINEHQAVA ESAIVGFPHD
     IKGNALYGFV ILKETGEVRN KENLTKEINQ YISDHIGPIA KLDKIQFVSG LPKTRSGKIM
     RRILRKIAEG DFSNFGDTTT LLNPEVVEQI MKERIA
//