Reviewed, UniProtKB/Swiss-Prot A5FC71 (UXUA_FLAJ1)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	Fjoh_4191

Organism

Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]

Taxonomic identifier

376686 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteria › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	Mannonate dehydratase HAMAP MF_00106		PRO_1000075900

Sequences

	Sequence		Length	Mass (Da)
	A5FC71-1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 824BA76B5266F3D5	FASTA	394	44,363
	10 20 30 40 50 60 MEQTLRWFGP NDPVSLQDIA QTGATGIVTA LHHIPNGEVW SIDEIIKRKV EIEHQDGDPK 70 80 90 100 110 120 KGASGLTWSV VESIPVHEDI KKQTGNYIQY IENYKESIRN LALCGIKCVC YNFMPVLDWS 130 140 150 160 170 180 RTDLSYTVED GSKALRFDIN AFAAFELFIL KRPGAENEYS DEQKQKAKSY FEAMTAEDKV 190 200 210 220 230 240 KLQQNILAGL PGAEEAYTVE DFLVTLSAYN HIDRQALKNN LFHFLKEIVP VAESKGVLMA 250 260 270 280 290 300 IHPDDPPYPI LGLPRVVSTE EDLIELMNAA PSKSNGFTMC TGSYGVRADN DLPGIVRRHG 310 320 330 340 350 360 DKMNFIHLRS TQRDEEGSFY EANHLEGDVD MYEVVKAILE VEKRNNSKLP MRPDHGHQML 370 380 390 DDLKKKTNPG YSAIGRLRGL AELRGLELGI KRSL

References

[1]

"Complete sequence of Flavobacterium johnsoniae UW101." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000685 Genomic DNA. Translation: ABQ07199.1.
RefSeq	YP_001196518.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5FC71.
Genome annotation databases
GeneID	5093821.
GenomeReviews	Gene locus Fjoh_4191 in contig CP000685_GR.
KEGG	fjo:Fjoh_4191.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1312.
HOGENOM	HBG585927.
OMA	VHEEIKT.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_FLAJ1

Accession

Primary (citable) accession number: A5FC71

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	June 12, 2007
Last modified:	February 9, 2010
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)