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A5FC71 (UXUA_FLAJ1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:Fjoh_4191
OrganismFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae) [Complete proteome] [HAMAP]
Taxonomic identifier376686 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Mannonate dehydratase HAMAP MF_00106
PRO_1000075900

Sequences

Sequence LengthMass (Da)Tools
A5FC71 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 824BA76B5266F3D5

FASTA39444,363
        10         20         30         40         50         60 
MEQTLRWFGP NDPVSLQDIA QTGATGIVTA LHHIPNGEVW SIDEIIKRKV EIEHQDGDPK 

        70         80         90        100        110        120 
KGASGLTWSV VESIPVHEDI KKQTGNYIQY IENYKESIRN LALCGIKCVC YNFMPVLDWS 

       130        140        150        160        170        180 
RTDLSYTVED GSKALRFDIN AFAAFELFIL KRPGAENEYS DEQKQKAKSY FEAMTAEDKV 

       190        200        210        220        230        240 
KLQQNILAGL PGAEEAYTVE DFLVTLSAYN HIDRQALKNN LFHFLKEIVP VAESKGVLMA 

       250        260        270        280        290        300 
IHPDDPPYPI LGLPRVVSTE EDLIELMNAA PSKSNGFTMC TGSYGVRADN DLPGIVRRHG 

       310        320        330        340        350        360 
DKMNFIHLRS TQRDEEGSFY EANHLEGDVD MYEVVKAILE VEKRNNSKLP MRPDHGHQML 

       370        380        390 
DDLKKKTNPG YSAIGRLRGL AELRGLELGI KRSL

« Hide

References

[1]"Complete sequence of Flavobacterium johnsoniae UW101."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Xie G., McBride M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17061 / DSM 2064 / UW101.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000685 Genomic DNA. Translation: ABQ07199.1.
RefSeqYP_001196518.1. NC_009441.1.

3D structure databases

ProteinModelPortalA5FC71.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5FC71.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5093821.
GenomeReviewsGene locus Fjoh_4191 in contig CP000685_GR.
KEGGfjo:Fjoh_4191.
PATRIC21902987. VBIFlaJoh53613_4336.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
HOGENOMHBG585927.
OMAVHEEIKT.

Enzyme and pathway databases

BioCycFJOH376686:FJOH_4191-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_FLAJ1
AccessionPrimary (citable) accession number: A5FC71
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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