A5F8G9 (ACYP_VIBC3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	VC0395_A0969, VC395_1474

Organism

Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395) [Complete proteome] [HAMAP]

Taxonomic identifier

345073 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.
Caution	Lacks the conserved active site Arg in position 20. There is a cysteine in this position.
Sequence caution	The sequence ABQ21959.1 differs from that shown. Reason: Erroneous initiation. The sequence ACP09482.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Acylphosphatase HAMAP MF_01450		PRO_0000326840
Regions
	Domain	5 – 91	87	Acylphosphatase-like
Sites
	Active site	38	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5F8G9 [UniParc]. Last modified April 8, 2008. Version 2. Checksum: 40A67A424AB36C66	FASTA	91	10,226
	10 20 30 40 50 60 MEKQCSKFIV SGHVQGVGFC YHTSHQGLKL GLTGYAKNLN NGDVEVVACG TPERLEELYL 70 80 90 WLQEGPKTAS VRQVRRLSSE LEHDYQGFEI L

References

[1]	Heidelberg J. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395.
[2]	"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000627 Genomic DNA. Translation: ABQ21959.1. Different initiation. CP001235 Genomic DNA. Translation: ACP09482.1. Different initiation.
3D structure databases
ProteinModelPortal	A5F8G9.
ModBase	Search...
Protein-protein interaction databases
STRING	A5F8G9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus VC0395_A0969 in contig CP000627_GR. Gene locus VC395_1474 in contig CP001235_GR.
KEGG	vco:VC0395_A0969.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1254.
HOGENOM	HBG750266.
ProtClustDB	PRK14426.
Enzyme and pathway databases
BioCyc	VCHO345073:VC0395_A0969-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. False negative. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_VIBC3

Accession

Primary (citable) accession number: A5F8G9
Secondary accession number(s): C3M0B6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	November 16, 2011
This is version 30 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program