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Protein

Glycogen synthase

Gene

glgA

Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei18ADP-glucoseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processGlycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:VC0395_A1329, VC395_1843
OrganismiVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Taxonomic identifieri345073 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000249 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000724161 – 484Glycogen synthaseAdd BLAST484

Interactioni

Protein-protein interaction databases

STRINGi345073.VC0395_A1329.

Structurei

3D structure databases

ProteinModelPortaliA5F7G0.
SMRiA5F7G0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CXW. Bacteria.
COG0297. LUCA.
HOGENOMiHOG000294940.
KOiK00703.
OMAiCAPVIKA.
OrthoDBiPOG091H08HW.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth. 1 hit.
InterProiView protein in InterPro
IPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
PfamiView protein in Pfam
PF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

A5F7G0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQFNVWFTV SEVQGLVKSG GLADVAKALP QALKALHQQV AIALPAYRSV
60 70 80 90 100
PGKEDAELVL ETELTHWPHT QYRVLKRDLD GVPIYLIDCP AYFDRPALYA
110 120 130 140 150
ENNQAYADNG ERFGFFSAAC LDVLPKLGIQ PDIIHANDWH TGLVPFLLKT
160 170 180 190 200
RYRYDSFFEQ VKSVLTVHNA IFKGIFSYHQ LEVIPELNLS GMEFLQYGHD
210 220 230 240 250
HVSMLRAGIA FADKVNAVSP NYAAELLTPL GAHGLVDDFV RRARDLHGIV
260 270 280 290 300
NGCDYSEWNP RTDHYLPATY SDEPESMRKG KALCKTALQE ELHLPVTDVP
310 320 330 340 350
LFGMVCRLTH QKGFHYLLPI LEQFLRNNVQ VVIVGTGEPE VAARLNKIAH
360 370 380 390 400
YHRAKFAFVE TYSERLAHWV EAGSDFFLMP SEFEACGLNQ IYSMAYGTLP
410 420 430 440 450
IVREVGGLKD TVNDYDKFPE RATGFGYQEP TPEALLITMQ RALLFYLQQP
460 470 480
EEMLKVQQRA MQQNFSWEES AQEYMKMYRL ARFG
Length:484
Mass (Da):55,067
Last modified:June 12, 2007 - v1
Checksum:i776D1D3E6BCC0920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000627 Genomic DNA. Translation: ABQ19573.1.
CP001235 Genomic DNA. Translation: ACP09840.1.
RefSeqiWP_000434699.1. NC_012582.1.

Genome annotation databases

EnsemblBacteriaiABQ19573; ABQ19573; VC0395_A1329.
ACP09840; ACP09840; VC395_1843.
KEGGivco:VC0395_A1329.
vcr:VC395_1843.
PATRICifig|345073.21.peg.1786.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiGLGA_VIBC3
AccessioniPrimary (citable) accession number: A5F7G0
Secondary accession number(s): C3M1C4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 12, 2007
Last modified: June 7, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families