A5F579 (CYSD_VIBC3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	VC0395_A2137, VC395_2672

Organism

Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395) [Complete proteome] [HAMAP]

Taxonomic identifier

345073 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000071168

Sequences

	Sequence		Length	Mass (Da)
	A5F579 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 728962CE65C5DEAA	FASTA	302	35,043
	10 20 30 40 50 60 MDQQRLTHLK QLEAESIHII REVAAEFDNP VMMYSIGKDS SVMLHLTRKA FYPGKIPFPL 70 80 90 100 110 120 LHVDTDWKFR DMITFRDATA KKYGFDLIVH KNPEGLAAGI NPFDHGSSKH TDIMKTQGLK 130 140 150 160 170 180 QALNKYGFDA AFGGARRDEE KSRAKERVYS FRDKNHTWDP KNQRPELWRT YNGQINKGES 190 200 210 220 230 240 IRVFPLSNWT ELDIWQYIYL ENIEIVPLYL ADVRPVVQRD GMLIMVDDDR MKLREGEQIE 250 260 270 280 290 300 HKSVRFRTLG CYPLTGAIES QANTLTEIIE EMLVATSSER QGRAIDHDQS GSMELKKRQG YF

References

[1]	Heidelberg J. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395.
[2]	"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000627 Genomic DNA. Translation: ABQ20682.1. CP001235 Genomic DNA. Translation: ACP10658.1.
3D structure databases
ProteinModelPortal	A5F579.
SMR	A5F579. Positions 5-211.
ModBase	Search...
Protein-protein interaction databases
STRING	A5F579.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus VC0395_A2137 in contig CP000627_GR. Gene locus VC395_2672 in contig CP001235_GR.
KEGG	vco:VC0395_A2137.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	RVIDHDA.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	VCHO345073:VC0395_A2137-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_VIBC3

Accession

Primary (citable) accession number: A5F579
Secondary accession number(s): C3LXF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	June 12, 2007
Last modified:	November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program