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A5F292 (A5F292_VIBC3) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=1.1.1.42 EMBL ABQ19957.1

NADP-dependent isocitrate dehydrogenase EMBL ACP09218.1
EC=1.1.1.42 EMBL ACP09218.1
Gene names
Name:icd EMBL ABQ19957.1
Ordered Locus Names:VC0395_A0711 EMBL ABQ19957.1, VC395_1208 EMBL ACP09218.1
OrganismVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) [Complete proteome] [HAMAP] EMBL ABQ19957.1
Taxonomic identifier345073 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length741 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region134 – 1418Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3521Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5501Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5541Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1471Substrate By similarity PIRSR PIRSR009407-2
Binding site5491Substrate By similarity PIRSR PIRSR009407-2
Site2571Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4221Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
A5F292 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 9442576499BA54A7

FASTA74180,531
        10         20         30         40         50         60 
MPTNKPTIIY TITDEAPALA TYSLLPIIQS FTASSGINVE TRDISLAGRI LANFPEHLTE 

        70         80         90        100        110        120 
EQRISDALTE LGELAKTPEA NIIKLPNISA SVPQLKAAIK ELQDKGYALP NYPEEPSSYE 

       130        140        150        160        170        180 
EEAIKATYDK IKGSAVNPVL REGNSDRRAP ASVKNYAKKN PHSMGAWSKD SKSHVASMSD 

       190        200        210        220        230        240 
KDFFGSEKSM TVSGATKVAI EFVGKEGAVK VLKKPFALQD KEIIDTSVMS KKALIAFFEK 

       250        260        270        280        290        300 
EIADAKAQDV LFSLHMKATM MKVSDPVIFG HAVKVYYKAV FDKYGQLFDQ LGVDVNNGLG 

       310        320        330        340        350        360 
DVYAKIQSLP EAQRAEIEAA IQAVYATQPA LAMVDSDRGI TNLHVPSDVI VDASMPAMIR 

       370        380        390        400        410        420 
TSGQMWGPDG KQKDTKATIP DRCYAGVYQT VIDFCKQHGA FDPTTMGSVP NVGLMAQKAE 

       430        440        450        460        470        480 
EYGSHDKTFI LDAEGVVRVI DEAGKVLLEQ SVEAGDIFRM CQVKDAPIQD WVKLAVTRAR 

       490        500        510        520        530        540 
ASNTPAVFWL DPARAHDAEL IKKVNQYLPN HDTSGLEIKI LSPIEATQYS LVRMKAGQDT 

       550        560        570        580        590        600 
ISVTGNVLRD YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVQQVQKENH 

       610        620        630        640        650        660 
LRWDSLGEFL ALAASLEHLS VVTGNRKAQV LADALDKATG KFLDMNKSPS RRVGEIDNRG 

       670        680        690        700        710        720 
SHFYLATYWA QALAEQTADA DLAAEFAPIA KALEEKEAQI VAELNGAQGK PGDLGGYYAP 

       730        740 
EFAKVAPLMR PSSTFNAIID R 

« Hide

References

[1]Heidelberg J.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 39541 / Classical Ogawa 395 / O395 and O395 EMBL ABQ19957.1.
[2]"A recalibrated molecular clock and independent origins for the cholera pandemic clones."
Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 39541 / Classical Ogawa 395 / O395 and O395 EMBL ACP09218.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000627 Genomic DNA. Translation: ABQ19957.1.
CP001235 Genomic DNA. Translation: ACP09218.1.
RefSeqYP_001216661.1. NC_009457.1.
YP_002819454.1. NC_012582.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING345073.VC0395_A0711.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ19957; ABQ19957; VC0395_A0711.
ACP09218; ACP09218; VC395_1208.
GeneID5137167.
7775156.
KEGGvco:VC0395_A0711.
vcr:VC395_1208.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2838.
HOGENOMHOG000240860.
KOK00031.
OMAGYLRWDS.
ProtClustDBCLSK867411.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5F292_VIBC3
AccessionPrimary (citable) accession number: A5F292
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)