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Protein
Submitted name:

Putative glutamate decarboxylase

Gene

VC0395_A0719

Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. carboxy-lyase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. carboxylic acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative glutamate decarboxylaseImported
Gene namesi
Ordered Locus Names:VC0395_A0719Imported, VC395_1216Imported
OrganismiVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)Imported
Taxonomic identifieri345073 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000000249: Chromosome 2, UP000001630: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi345073.VC0395_A0719.

Structurei

3D structure databases

ProteinModelPortaliA5F283.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000282553.
KOiK01580.
OMAiSEEAHYC.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR022517. Asp_decarboxylase_pyridox.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR03799. NOD_PanD_pyr. 1 hit.

Sequencei

Sequence statusi: Complete.

A5F283-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSEHKSAQV NFDSLLKIFT VPEGPDSTLT KIDEELSRNL NHFLRKHIVA
60 70 80 90 100
EEKPLKEIEK DFSNAHIPEQ PQFVSDHTQY LLDTLVSHSV HTASPSFIGH
110 120 130 140 150
MTSALPYFLM PLSKIMIALN QNLVKIETSK AFTPLERQVL GMIHRLIYGE
160 170 180 190 200
TDHFYQQWMH SAEHSLGAFC SGGTIANITA LWVARNNALK AEGDFPGVEK
210 220 230 240 250
AGLFKAMRHY GHEGLAILVS ERGHYSLKKA ADVLGIGQEG LVAVKTDAHN
260 270 280 290 300
RICPHDLEQK ITELKANKIK VFAVVGVAGT TETGNIDPLR TIAQICQREQ
310 320 330 340 350
IHFHIDAAWG GATLMSNRYR GLLDGVELAD SVTIDAHKQL YIPMGAGMVL
360 370 380 390 400
FKDPNAMRSI EHHAQYILRQ GSKDLGSHTL EGSRSGMAML VYASMHIISR
410 420 430 440 450
PGYQLLIDQS IEKARYFADL IDAQTDFELV SQPELCLLTY RYLPEHVRMA
460 470 480 490 500
LEKSQGVQRA QLNELLNELT KFIQKKQRET GKSFVSRTQL NPHQWDKLAT
510 520 530 540
IVFRVVLANP LTTKEILHNV LDEQREIAQQ APKLMRQIEH LTQCILNQ
Length:548
Mass (Da):61,693
Last modified:June 12, 2007 - v1
Checksum:iDCBFD48556AF50B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000627 Genomic DNA. Translation: ABQ20604.1.
CP001235 Genomic DNA. Translation: ACP09226.1.
RefSeqiYP_001216669.1. NC_009457.1.
YP_002819462.1. NC_012582.1.

Genome annotation databases

EnsemblBacteriaiABQ20604; ABQ20604; VC0395_A0719.
ACP09226; ACP09226; VC395_1216.
GeneIDi5137142.
7775164.
KEGGivco:VC0395_A0719.
vcr:VC395_1216.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000627 Genomic DNA. Translation: ABQ20604.1.
CP001235 Genomic DNA. Translation: ACP09226.1.
RefSeqiYP_001216669.1. NC_009457.1.
YP_002819462.1. NC_012582.1.

3D structure databases

ProteinModelPortaliA5F283.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi345073.VC0395_A0719.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ20604; ABQ20604; VC0395_A0719.
ACP09226; ACP09226; VC395_1216.
GeneIDi5137142.
7775164.
KEGGivco:VC0395_A0719.
vcr:VC395_1216.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000282553.
KOiK01580.
OMAiSEEAHYC.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR022517. Asp_decarboxylase_pyridox.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR03799. NOD_PanD_pyr. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Heidelberg J.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39541 / Classical Ogawa 395 / O395Imported and O395Imported.
  2. "A recalibrated molecular clock and independent origins for the cholera pandemic clones."
    Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
    PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39541 / Classical Ogawa 395 / O395 and O395Imported.

Entry informationi

Entry nameiA5F283_VIBC3
AccessioniPrimary (citable) accession number: A5F283
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: January 7, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.