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Protein

Putative phosphoenolpyruvate synthase regulatory protein

Gene

VC0395_0252

Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

Catalytic activityi

ADP + [pyruvate, water dikinase] = AMP + [pyruvate, water dikinase] phosphate.UniRule annotation
[Pyruvate, water dikinase] phosphate + phosphate = [pyruvate, water dikinase] + diphosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi157 – 1648ADPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phosphoenolpyruvate synthase regulatory proteinUniRule annotation (EC:2.7.11.33UniRule annotation, EC:2.7.4.28UniRule annotation)
Short name:
PEP synthase regulatory proteinUniRule annotation
Short name:
PSRPUniRule annotation
Alternative name(s):
Pyruvate, water dikinase regulatory proteinUniRule annotation
Gene namesi
Ordered Locus Names:VC0395_0252, VC395_A1010
OrganismiVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Taxonomic identifieri345073 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000249 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 277277Putative phosphoenolpyruvate synthase regulatory proteinPRO_1000073012Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi345073.VC0395_0252.

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CF9. Bacteria.
COG1806. LUCA.
HOGENOMiHOG000218053.
KOiK09773.
OMAiYAQCEFE.

Family and domain databases

HAMAPiMF_01062. PSRP.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026530. PSRP.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5F0Z4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMESQRRDV FYVSDGTAIT CETLGHVVLG QFAVQPNEKT FPFVESDEKL
60 70 80 90 100
SELLKQIQRS YQLHGVKPLV FFSMVIPEMR TRLLQAPAHF YDVLESIVQR
110 120 130 140 150
VSLDIEMEPA PKLQRSRSVG KDSDTYFDRI AAIEYTLAHD DGVSLKDLDR
160 170 180 190 200
ADIILLGVSR SGKTPTSLYM AMQFGLRVVN YPFIAEDMHA MRLLPEFEFH
210 220 230 240 250
RHKLFGLTIN AERLTEIREN RLAGSEYASN QQCQQELATV EALFRREAIS
260 270
YINTSSLSVE EISTRILERT GLKRRLF
Length:277
Mass (Da):31,801
Last modified:June 12, 2007 - v1
Checksum:i14DE2BD2696A3B97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000626 Genomic DNA. Translation: ABQ18905.1.
CP001236 Genomic DNA. Translation: ACP11840.1.
RefSeqiWP_001177874.1. NC_012583.1.

Genome annotation databases

EnsemblBacteriaiABQ18905; ABQ18905; VC0395_0252.
ACP11840; ACP11840; VC395_A1010.
KEGGivco:VC0395_0252.
vcr:VC395_A1010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000626 Genomic DNA. Translation: ABQ18905.1.
CP001236 Genomic DNA. Translation: ACP11840.1.
RefSeqiWP_001177874.1. NC_012583.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi345073.VC0395_0252.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ18905; ABQ18905; VC0395_0252.
ACP11840; ACP11840; VC395_A1010.
KEGGivco:VC0395_0252.
vcr:VC395_A1010.

Phylogenomic databases

eggNOGiENOG4105CF9. Bacteria.
COG1806. LUCA.
HOGENOMiHOG000218053.
KOiK09773.
OMAiYAQCEFE.

Family and domain databases

HAMAPiMF_01062. PSRP.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026530. PSRP.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Heidelberg J.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39541 / Classical Ogawa 395 / O395.
  2. "A recalibrated molecular clock and independent origins for the cholera pandemic clones."
    Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
    PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39541 / Classical Ogawa 395 / O395.

Entry informationi

Entry nameiPSRP_VIBC3
AccessioniPrimary (citable) accession number: A5F0Z4
Secondary accession number(s): C3M6S7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 12, 2007
Last modified: November 11, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.