SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A5F0H0

- A5F0H0_VIBC3

UniProt

A5F0H0 - A5F0H0_VIBC3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Biosynthetic arginine decarboxylase

Gene
speA, VC0395_0419, VC395_A0839
Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the biosynthesis of agmatine from arginine By similarity.UniRule annotation

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations
Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. arginine catabolic process Source: InterPro
  2. spermidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotationSAAS annotations, Lyase

Keywords - Biological processi

Polyamine biosynthesisUniRule annotation, Spermidine biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotation, Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

UniPathwayiUPA00186; UER00284.

Names & Taxonomyi

Protein namesi
Recommended name:
Biosynthetic arginine decarboxylaseUniRule annotation (EC:4.1.1.19UniRule annotation)
Short name:
ADCUniRule annotation
Gene namesi
Name:speAUniRule annotationImported
Ordered Locus Names:VC0395_0419Imported, VC395_A0839Imported
OrganismiVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)Imported
Taxonomic identifieri345073 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000001630: Chromosome II

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei126 – 1261N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi345073.VC0395_0419.

Structurei

3D structure databases

ProteinModelPortaliA5F0H0.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni311 – 32111Substrate-binding By similarityUniRule annotationAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1166.
HOGENOMiHOG000029191.
KOiK01585.
OMAiIDHYVDG.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01417. SpeA.
InterProiIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSiPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMiSSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR01273. speA. 1 hit.

Sequencei

Sequence statusi: Complete.

A5F0H0-1 [UniParc]FASTAAdd to Basket

« Hide

MTSRVSGVIS TDEIIVILSV FVRYDVEQPS KLDRVRADYN VHYWSQGFFG    50
IDDQGEVYVS PRKDKAHQTQ LSSIVKQLEA RDLNLPVLVR FPQILHQRVH 100
NICDAFNQAI EEYDYPNKYL LVYPIKVNQQ KEVVDEILAS QAELEHKQLG 150
LEAGSKPELL AVLAMAQQAS SVIVCNGYKD REYIRLALIG EKLGHKVFIV 200
LEKLSELDLV LKEAKSLGVK PRLGLRIRLA SQGAGKWQSS GGEKSKFGLA 250
ASQVLTVINR LKAENQLEAL QLVHFHLGSQ MANIRDVRNG VNEAVRFYCE 300
LRELGAHIDF FDVGGGLAVD YDGTRSQSSN SMNYGLHEYA RNIVSTVSDV 350
CNLYGQPRPV IISESGRSIT AHHAVLITNV IGTEAYSPEE IPAPGADAPM 400
LLKNMWRGFE EVQHGTDDRA LIEIYNDTQS DLSEAHSQFA TGVLNLEHRA 450
WAEQLSLRIY HELRQKMSNK NRFHRPILDE LQERLADKFF VNFSLFQSLP 500
DAWGIDQVFP VLPLSGLEEM NDRRAVMLDI TCDSDGAVEQ YVEGQGIEST 550
LPVPAWTSDK PYLMGFFLVG AYQEILGDMH NLFGDTHSAV VNINDNGESE 600
IAFINEGDTV EDMMRYVHID VDKIRTNYRQ LVSQRVAKEE QETVLAELEL 650
GLSGYTYLED F 661
Length:661
Mass (Da):74,465
Last modified:June 12, 2007 - v1
Checksum:i44F4E37A2D81AC43
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000626 Genomic DNA. Translation: ABQ19043.1.
CP001236 Genomic DNA. Translation: ACP11672.1.
RefSeqiYP_001215260.1. NC_009456.1.
YP_002821908.1. NC_012583.1.

Genome annotation databases

EnsemblBacteriaiABQ19043; ABQ19043; VC0395_0419.
ACP11672; ACP11672; VC395_A0839.
GeneIDi5134840.
7777902.
KEGGivco:VC0395_0419.
vcr:VC395_A0839.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000626 Genomic DNA. Translation: ABQ19043.1 .
CP001236 Genomic DNA. Translation: ACP11672.1 .
RefSeqi YP_001215260.1. NC_009456.1.
YP_002821908.1. NC_012583.1.

3D structure databases

ProteinModelPortali A5F0H0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 345073.VC0395_0419.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ19043 ; ABQ19043 ; VC0395_0419 .
ACP11672 ; ACP11672 ; VC395_A0839 .
GeneIDi 5134840.
7777902.
KEGGi vco:VC0395_0419.
vcr:VC395_A0839.

Phylogenomic databases

eggNOGi COG1166.
HOGENOMi HOG000029191.
KOi K01585.
OMAi IDHYVDG.

Enzyme and pathway databases

UniPathwayi UPA00186 ; UER00284 .

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01417. SpeA.
InterProi IPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSi PR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMi SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR01273. speA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Heidelberg J.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39541 / Classical Ogawa 395 / O395 and O395Imported.
  2. "A recalibrated molecular clock and independent origins for the cholera pandemic clones."
    Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
    PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39541 / Classical Ogawa 395 / O395 and O395Imported.

Entry informationi

Entry nameiA5F0H0_VIBC3
AccessioniPrimary (citable) accession number: A5F0H0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: September 3, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi