A5EZR7 (GLPB_VIBC3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	VC0395_0687, VC395_A0565

Organism

Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395) [Complete proteome] [HAMAP]

Taxonomic identifier

345073 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP MF_00753
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP MF_00753
Cofactor	FMN By similarity. HAMAP MF_00753
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP MF_00753
Subunit structure	Composed of a catalytic glpA/B dimer and of membrane bound glpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 436	436	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP MF_00753		PRO_1000072826

Sequences

	Sequence		Length	Mass (Da)
	A5EZR7 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 841AE0376A41D557	FASTA	436	48,030
	10 20 30 40 50 60 MMHYDVAVIG GGIAGYSAAL RALQAGKKVV LINQGQSALH FSSGSIDVLG RLPDGSVVNQ 70 80 90 100 110 120 PFDALSALQQ QVPEHPYSKV GRKNSEKGLM WFKRTLDSAH VPLHHEPDGA NHWRITPLGT 130 140 150 160 170 180 LKNTWLSQPF VYPYRGNADF SRIVIVAIDG YRDFQPAMLR DNLAQRPELA NTPMLTVNVS 190 200 210 220 230 240 IPGFEGFRRN PNELRSIDIA RLLRQESAWN ALCDQLMRVA RPDDLVIMPA IMGNGDGLHL 250 260 270 280 290 300 MTKLQQVTQL RFHEVPTMPP SLLGIRIEEA LHRSFIQGGG VQLKGDKVIG GDFAGSRLTA 310 320 330 340 350 360 IHTQNLRDFP ISAEHYVMAT GSYFSQGLQA SQHAIQEPTF ALDVQQNPDR AQWRHAQFIA 370 380 390 400 410 420 AQSHPFMTFG VITDANLHPS RQGKTIDNLW CCGAMLSGYD PVFEGCGGGV AIATAYHAVE 430 QILATYAQTK QPEVLL

References

[1]	Heidelberg J. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395.
[2]	"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000626 Genomic DNA. Translation: ABQ18464.1. CP001236 Genomic DNA. Translation: ACP11399.1.
3D structure databases
ProteinModelPortal	A5EZR7.
ModBase	Search...
Protein-protein interaction databases
STRING	A5EZR7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus VC0395_0687 in contig CP000626_GR. Gene locus VC395_A0565 in contig CP001236_GR.
KEGG	vco:VC0395_0687.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3075.
HOGENOM	HBG297155.
OMA	LEHKLAF.
ProtClustDB	PRK05329.
Enzyme and pathway databases
BioCyc	VCHO345073:VC0395_0687-MONOMER.
Family and domain databases
HAMAP	MF_00753. Glycerol3P_GlpB. [Tree]
InterPro	IPR003953. FAD_bind2_N. IPR009158. G3P_DH_anaerobic_bsu. [Graphical view]
KO	K00112.
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. Glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_VIBC3

Accession

Primary (citable) accession number: A5EZR7
Secondary accession number(s): C3M5I6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	June 12, 2007
Last modified:	November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program