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A5EZR7 (GLPB_VIBC3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3
Gene names
Name:glpB
Ordered Locus Names:VC0395_0687, VC395_A0565
OrganismVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) [Complete proteome] [HAMAP]
Taxonomic identifier345073 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753

Cofactor

FMN By similarity. HAMAP-Rule MF_00753

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753

Subunit structure

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.

Sequence similarities

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
   LigandFlavoprotein
FMN
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 436436Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753
PRO_1000072826

Sequences

Sequence LengthMass (Da)Tools
A5EZR7 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 841AE0376A41D557

FASTA43648,030
        10         20         30         40         50         60 
MMHYDVAVIG GGIAGYSAAL RALQAGKKVV LINQGQSALH FSSGSIDVLG RLPDGSVVNQ 

        70         80         90        100        110        120 
PFDALSALQQ QVPEHPYSKV GRKNSEKGLM WFKRTLDSAH VPLHHEPDGA NHWRITPLGT 

       130        140        150        160        170        180 
LKNTWLSQPF VYPYRGNADF SRIVIVAIDG YRDFQPAMLR DNLAQRPELA NTPMLTVNVS 

       190        200        210        220        230        240 
IPGFEGFRRN PNELRSIDIA RLLRQESAWN ALCDQLMRVA RPDDLVIMPA IMGNGDGLHL 

       250        260        270        280        290        300 
MTKLQQVTQL RFHEVPTMPP SLLGIRIEEA LHRSFIQGGG VQLKGDKVIG GDFAGSRLTA 

       310        320        330        340        350        360 
IHTQNLRDFP ISAEHYVMAT GSYFSQGLQA SQHAIQEPTF ALDVQQNPDR AQWRHAQFIA 

       370        380        390        400        410        420 
AQSHPFMTFG VITDANLHPS RQGKTIDNLW CCGAMLSGYD PVFEGCGGGV AIATAYHAVE 

       430 
QILATYAQTK QPEVLL 

« Hide

References

[1]Heidelberg J.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 39541 / Classical Ogawa 395 / O395.
[2]"A recalibrated molecular clock and independent origins for the cholera pandemic clones."
Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 39541 / Classical Ogawa 395 / O395.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000626 Genomic DNA. Translation: ABQ18464.1.
CP001236 Genomic DNA. Translation: ACP11399.1.
RefSeqYP_001215526.1. NC_009456.1.
YP_002821635.1. NC_012583.1.

3D structure databases

ProteinModelPortalA5EZR7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING345073.VC0395_0687.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ18464; ABQ18464; VC0395_0687.
ACP11399; ACP11399; VC395_A0565.
GeneID5134955.
7777629.
KEGGvco:VC0395_0687.
vcr:VC395_A0565.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3075.
HOGENOMHOG000278489.
KOK00112.
OMAFRSVNIS.
ProtClustDBPRK05329.

Enzyme and pathway databases

UniPathwayUPA00618; UER00673.

Family and domain databases

HAMAPMF_00753. Glycerol3P_GlpB.
InterProIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsTIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLPB_VIBC3
AccessionPrimary (citable) accession number: A5EZR7
Secondary accession number(s): C3M5I6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 12, 2007
Last modified: April 16, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways