A5EZ03 (A5EZ03_VIBC3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Name:	gcvT EMBL ABQ18764.1
Ordered Locus Names:	VC0395_0949, VC395_A0317

Organism

Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395) [Complete proteome] [HAMAP]

Taxonomic identifier

345073 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. SAAS SAAS006223 RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase SAAS SAAS006223 RuleBase RU003981 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5EZ03 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 71F698C70027DB25	FASTA	376	40,568
	10 20 30 40 50 60 MTEQHETLLT TPLHALHIEV GAKMVPFAGY DMPVQYALGV KKEHIHTREA AGLFDVSHMG 70 80 90 100 110 120 QLRLYGAQAA AALEALVPVD IIDLPVGKQR YAFFTNAQGG IMDDLMVANM GDHLFVVVNA 130 140 150 160 170 180 ACKAQDIAHL KAHLPADVEM EVIEDRALLA LQGPKAAQVL ARLQPAVAKM LFMDVQLLEI 190 200 210 220 230 240 DGAECIVSRS GYTGEDGYEI SVPADKAAAL ARKLTDFEEV EWIGLGARDS LRLECGLCLY 250 260 270 280 290 300 GHDLDPTTTP VEASLLWAIQ PVRRKGGARE GGFPGAEIIL SQIETKQVSR KRVGLIGQTK 310 320 330 340 350 360 APVREGTELF DAQGNKIGIV TSGTAGPTAD KPVSMAYVST EHAALGGEVF ADVRGKMLPM 370 TVEKMPFVPQ RYYRGA

References

[1]	"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395 [Nankai/TEDA].
[2]	Heidelberg J. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395 [TIGR].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000626 Genomic DNA. Translation: ABQ18764.1. CP001236 Genomic DNA. Translation: ACP11157.1.
3D structure databases
ProteinModelPortal	A5EZ03.
ModBase	Search...
Protein-protein interaction databases
STRING	A5EZ03.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus VC0395_0949 in contig CP000626_GR. Gene locus VC395_A0317 in contig CP001236_GR.
KEGG	vco:VC0395_0949.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	MPVQYPL.
ProtClustDB	CLSK910129.
Enzyme and pathway databases
BioCyc	VCHO345073:VC0395_0949-MONOMER.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5EZ03_VIBC3

Accession

Primary (citable) accession number: A5EZ03

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)