A5EYU8 (A5EYU8_VIBC3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase 1 HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase 1 HAMAP MF_00020

Gene names

Name:	ackA-2 EMBL ABQ19406.1
Synonyms:	ackA1 HAMAP MF_00020
Ordered Locus Names:	VC0395_0994, VC395_A0272

Organism

Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395) [Complete proteome] [HAMAP]

Taxonomic identifier

345073 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. SAAS SAAS000890 HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. SAAS SAAS000890 HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. RuleBase RU003835 HAMAP MF_00020

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS000890 HAMAP MF_00020
Ligand	ATP-binding SAAS SAAS000890 HAMAP MF_00020 Nucleotide-binding
Molecular function	Kinase SAAS SAAS000890 RuleBase RU003835 HAMAP MF_00020 EMBL ABQ19406.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5EYU8 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 3419266AC328FD9D	FASTA	397	42,827
	10 20 30 40 50 60 MSNSYVLVIN SGSSSLKFAV IDSQTGEALI SGLGECFGMP EAVISWKYQG EKTEEAITAA 70 80 90 100 110 120 DHHHQHAINR IVGLMESLGF AQDLVAVGHR IVHGGEKFTS TVRIDEEVLA EIESLSDLAP 130 140 150 160 170 180 LHNPAGAIGI QAAMAAFPSL PQFAVFDTAF HQTMPKKAFT GAISHELYKQ YGIRRYGFHG 190 200 210 220 230 240 TSHYYVSREA AKMLNKPIEQ ASFISVHLGN GASVCAISNG QSVDTSMGFT PLAGLMMGTR 250 260 270 280 290 300 SGDLDPGIIE FLMKKGWSQE KVFETLNKKS GFLGVSGLTS DARGILEAME NGHEGAKLAF 310 320 330 340 350 360 EVFTYRVAKY IGSYLIPLDH LDAIIFTGGI GENSLPIRRE ILGNLKLLGF VEDEKGNEAA 370 380 390 RFGKAGIIAK SELLNAVAMV IPTNEEFVIA QQSVELL

References

[1]	"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395 [Nankai/TEDA].
[2]	Heidelberg J. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39541 / Ogawa 395 / O395 [TIGR].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000626 Genomic DNA. Translation: ABQ19406.1. CP001236 Genomic DNA. Translation: ACP11113.1.
3D structure databases
ProteinModelPortal	A5EYU8.
ModBase	Search...
Protein-protein interaction databases
STRING	A5EYU8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus VC0395_0994 in contig CP000626_GR. Gene locus VC395_A0272 in contig CP001236_GR.
KEGG	vco:VC0395_0994.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	AMEEGHE.
ProtClustDB	PRK12440.
Enzyme and pathway databases
BioCyc	VCHO345073:VC0395_0994-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5EYU8_VIBC3

Accession

Primary (citable) accession number: A5EYU8

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)