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A5EX62

- MUTS_DICNV

UniProt

A5EX62 - MUTS_DICNV

Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Dichelobacter nodosus (strain VCS1703A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    Functioni

    This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi613 – 6208ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. damaged DNA binding Source: UniProtKB-HAMAP
    3. mismatched DNA binding Source: InterPro

    GO - Biological processi

    1. mismatch repair Source: UniProtKB-HAMAP

    Keywords - Biological processi

    DNA damage, DNA repair

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDNOD246195:GHHS-1300-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA mismatch repair protein MutSUniRule annotation
    Gene namesi
    Name:mutSUniRule annotation
    Ordered Locus Names:DNO_1303
    OrganismiDichelobacter nodosus (strain VCS1703A)
    Taxonomic identifieri246195 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCardiobacterialesCardiobacteriaceaeDichelobacter
    ProteomesiUP000000248: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 861861DNA mismatch repair protein MutSPRO_0000335149Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi246195.DNO_1303.

    Structurei

    3D structure databases

    ProteinModelPortaliA5EX62.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the DNA mismatch repair MutS family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0249.
    HOGENOMiHOG000221407.
    KOiK03555.
    OMAiMMAQYLE.
    OrthoDBiEOG6Q5NPV.

    Family and domain databases

    Gene3Di3.30.420.110. 1 hit.
    3.40.1170.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00096. MutS.
    InterProiIPR005748. DNA_mismatch_repair_MutS-1.
    IPR007695. DNA_mismatch_repair_MutS-lik_N.
    IPR000432. DNA_mismatch_repair_MutS_C.
    IPR007861. DNA_mismatch_repair_MutS_clamp.
    IPR007696. DNA_mismatch_repair_MutS_core.
    IPR016151. DNA_mismatch_repair_MutS_N.
    IPR007860. DNA_mmatch_repair_MutS_con_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF01624. MutS_I. 1 hit.
    PF05188. MutS_II. 1 hit.
    PF05192. MutS_III. 1 hit.
    PF05190. MutS_IV. 1 hit.
    PF00488. MutS_V. 1 hit.
    [Graphical view]
    SMARTiSM00534. MUTSac. 1 hit.
    SM00533. MUTSd. 1 hit.
    [Graphical view]
    SUPFAMiSSF48334. SSF48334. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF53150. SSF53150. 1 hit.
    SSF55271. SSF55271. 1 hit.
    TIGRFAMsiTIGR01070. mutS1. 1 hit.
    PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5EX62-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTKISEHTP AMQQYLTIKE DFPDLLLFYR MGDFYELFFD DAKKAGALLN    50
    ITVTARGKIR GKPIPMAGVP AHALENYLAK LVKQGMSAVI CEQVGEVGKG 100
    LVERAVTRII TPGTLTDENL LDEARDSILL SLFCFQNNYF FAYADITRGD 150
    FQLTMGLNEQ ELQSEIERLR PAEILMPETA NVPAFITALK PHRQPDWYFD 200
    SDSSYRLICE YYQTTTIDGF GIAPDDPALS AAGCLLQYLH DTHKYHLPPL 250
    KPLQKQHDHQ YLLLDATTRR NLELEYTLNG ESKHSLIATI NRCSTAAGVR 300
    TLKRWINQPL IQHEYILERQ EAVTALLTHA DLDEIAKTLR ATADIERITT 350
    RIALQTAKPR ELAQLRDTLM QLPAINALLQ TSAAHSPLLA AATQALMHCP 400
    QLGDLLMKAL VEAPPLTLKE GGIFAAGYLP ELDALHELTD HSAQLLEKME 450
    QEEKAQTGLN TLKIGFNRVH GYYIDIPRSQ AANAPAHWIR RQTLKNSERY 500
    VTESLKTLEE RLLNAQDEAL ALEKQAYTEL LITLDKQRDD LYRLATALAE 550
    SDVLTCFARL AKEHHYCRPQ FSNQIEIQIT AGRHPVVEQL SAQPFIANDL 600
    VLHQKRQLLI LTGPNMGGKS TYMRQTALIV ILALAGSYVP AKEARIGRIN 650
    RIFTRIGASD DLAGGRSTFM VEMTETANIL NNADEHSLVI MDEIGRGTST 700
    FDGLSLAWAV ADHLLQKNRA LTLFATHYFE LTALVERHQH GANIHLSAAE 750
    DQEHIVFLYH IEEGATSKSY GLHVAKLAGV PQAVIHNANA KLRQLEEKRV 800
    PQRAHQALLP IESQKPSLSP QIKNILQQIQ EINPDELSPK AAHEWLYQLK 850
    TLVRDLDKNE L 861
    Length:861
    Mass (Da):96,680
    Last modified:June 12, 2007 - v1
    Checksum:i6FEE71BC9C0BF0B7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000513 Genomic DNA. Translation: ABQ13473.1.
    RefSeqiWP_012031593.1. NC_009446.1.
    YP_001210174.1. NC_009446.1.

    Genome annotation databases

    EnsemblBacteriaiABQ13473; ABQ13473; DNO_1303.
    GeneIDi5123365.
    KEGGidno:DNO_1303.
    PATRICi21786960. VBIDicNod48475_1292.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000513 Genomic DNA. Translation: ABQ13473.1 .
    RefSeqi WP_012031593.1. NC_009446.1.
    YP_001210174.1. NC_009446.1.

    3D structure databases

    ProteinModelPortali A5EX62.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246195.DNO_1303.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ13473 ; ABQ13473 ; DNO_1303 .
    GeneIDi 5123365.
    KEGGi dno:DNO_1303.
    PATRICi 21786960. VBIDicNod48475_1292.

    Phylogenomic databases

    eggNOGi COG0249.
    HOGENOMi HOG000221407.
    KOi K03555.
    OMAi MMAQYLE.
    OrthoDBi EOG6Q5NPV.

    Enzyme and pathway databases

    BioCyci DNOD246195:GHHS-1300-MONOMER.

    Family and domain databases

    Gene3Di 3.30.420.110. 1 hit.
    3.40.1170.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00096. MutS.
    InterProi IPR005748. DNA_mismatch_repair_MutS-1.
    IPR007695. DNA_mismatch_repair_MutS-lik_N.
    IPR000432. DNA_mismatch_repair_MutS_C.
    IPR007861. DNA_mismatch_repair_MutS_clamp.
    IPR007696. DNA_mismatch_repair_MutS_core.
    IPR016151. DNA_mismatch_repair_MutS_N.
    IPR007860. DNA_mmatch_repair_MutS_con_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF01624. MutS_I. 1 hit.
    PF05188. MutS_II. 1 hit.
    PF05192. MutS_III. 1 hit.
    PF05190. MutS_IV. 1 hit.
    PF00488. MutS_V. 1 hit.
    [Graphical view ]
    SMARTi SM00534. MUTSac. 1 hit.
    SM00533. MUTSd. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48334. SSF48334. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF53150. SSF53150. 1 hit.
    SSF55271. SSF55271. 1 hit.
    TIGRFAMsi TIGR01070. mutS1. 1 hit.
    PROSITEi PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: VCS1703A.

    Entry informationi

    Entry nameiMUTS_DICNV
    AccessioniPrimary (citable) accession number: A5EX62
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3