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A5EX62

- MUTS_DICNV

UniProt

A5EX62 - MUTS_DICNV

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Protein

DNA mismatch repair protein MutS

Gene
mutS, DNO_1303
Organism
Dichelobacter nodosus (strain VCS1703A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi613 – 6208ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. damaged DNA binding Source: UniProtKB-HAMAP
  3. mismatched DNA binding Source: InterPro

GO - Biological processi

  1. mismatch repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDNOD246195:GHHS-1300-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutS
Gene namesi
Name:mutS
Ordered Locus Names:DNO_1303
OrganismiDichelobacter nodosus (strain VCS1703A)
Taxonomic identifieri246195 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCardiobacterialesCardiobacteriaceaeDichelobacter
ProteomesiUP000000248: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 861861DNA mismatch repair protein MutSUniRule annotationPRO_0000335149Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi246195.DNO_1303.

Structurei

3D structure databases

ProteinModelPortaliA5EX62.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0249.
HOGENOMiHOG000221407.
KOiK03555.
OMAiMMAQYLE.
OrthoDBiEOG6Q5NPV.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5EX62-1 [UniParc]FASTAAdd to Basket

« Hide

MNTKISEHTP AMQQYLTIKE DFPDLLLFYR MGDFYELFFD DAKKAGALLN    50
ITVTARGKIR GKPIPMAGVP AHALENYLAK LVKQGMSAVI CEQVGEVGKG 100
LVERAVTRII TPGTLTDENL LDEARDSILL SLFCFQNNYF FAYADITRGD 150
FQLTMGLNEQ ELQSEIERLR PAEILMPETA NVPAFITALK PHRQPDWYFD 200
SDSSYRLICE YYQTTTIDGF GIAPDDPALS AAGCLLQYLH DTHKYHLPPL 250
KPLQKQHDHQ YLLLDATTRR NLELEYTLNG ESKHSLIATI NRCSTAAGVR 300
TLKRWINQPL IQHEYILERQ EAVTALLTHA DLDEIAKTLR ATADIERITT 350
RIALQTAKPR ELAQLRDTLM QLPAINALLQ TSAAHSPLLA AATQALMHCP 400
QLGDLLMKAL VEAPPLTLKE GGIFAAGYLP ELDALHELTD HSAQLLEKME 450
QEEKAQTGLN TLKIGFNRVH GYYIDIPRSQ AANAPAHWIR RQTLKNSERY 500
VTESLKTLEE RLLNAQDEAL ALEKQAYTEL LITLDKQRDD LYRLATALAE 550
SDVLTCFARL AKEHHYCRPQ FSNQIEIQIT AGRHPVVEQL SAQPFIANDL 600
VLHQKRQLLI LTGPNMGGKS TYMRQTALIV ILALAGSYVP AKEARIGRIN 650
RIFTRIGASD DLAGGRSTFM VEMTETANIL NNADEHSLVI MDEIGRGTST 700
FDGLSLAWAV ADHLLQKNRA LTLFATHYFE LTALVERHQH GANIHLSAAE 750
DQEHIVFLYH IEEGATSKSY GLHVAKLAGV PQAVIHNANA KLRQLEEKRV 800
PQRAHQALLP IESQKPSLSP QIKNILQQIQ EINPDELSPK AAHEWLYQLK 850
TLVRDLDKNE L 861
Length:861
Mass (Da):96,680
Last modified:June 12, 2007 - v1
Checksum:i6FEE71BC9C0BF0B7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000513 Genomic DNA. Translation: ABQ13473.1.
RefSeqiWP_012031593.1. NC_009446.1.
YP_001210174.1. NC_009446.1.

Genome annotation databases

EnsemblBacteriaiABQ13473; ABQ13473; DNO_1303.
GeneIDi5123365.
KEGGidno:DNO_1303.
PATRICi21786960. VBIDicNod48475_1292.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000513 Genomic DNA. Translation: ABQ13473.1 .
RefSeqi WP_012031593.1. NC_009446.1.
YP_001210174.1. NC_009446.1.

3D structure databases

ProteinModelPortali A5EX62.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 246195.DNO_1303.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ13473 ; ABQ13473 ; DNO_1303 .
GeneIDi 5123365.
KEGGi dno:DNO_1303.
PATRICi 21786960. VBIDicNod48475_1292.

Phylogenomic databases

eggNOGi COG0249.
HOGENOMi HOG000221407.
KOi K03555.
OMAi MMAQYLE.
OrthoDBi EOG6Q5NPV.

Enzyme and pathway databases

BioCyci DNOD246195:GHHS-1300-MONOMER.

Family and domain databases

Gene3Di 3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00096. MutS.
InterProi IPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view ]
SMARTi SM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view ]
SUPFAMi SSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsi TIGR01070. mutS1. 1 hit.
PROSITEi PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VCS1703A.

Entry informationi

Entry nameiMUTS_DICNV
AccessioniPrimary (citable) accession number: A5EX62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: September 3, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3