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Protein

60 kDa chaperonin

Gene

groL

Organism
Dichelobacter nodosus (strain VCS1703A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:DNO_1339
OrganismiDichelobacter nodosus (strain VCS1703A)
Taxonomic identifieri246195 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCardiobacterialesCardiobacteriaceaeDichelobacter
Proteomesi
  • UP000000248 Componenti: Chromosome

Subcellular locationi

A5EX17:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000257771 – 54760 kDa chaperoninAdd BLAST547

Proteomic databases

PRIDEiA5EX17.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi246195.DNO_1339.

Structurei

3D structure databases

ProteinModelPortaliA5EX17.
SMRiA5EX17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A5EX17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAKEVRFGE DARNKMLKGV NILADAVKVT LGPKGRNVIL DKSFGTPTVT
60 70 80 90 100
KDGVSVAKEI ELADKFENMG AQLVKEVASQ TNDAAGDGTT TATVLAQAIV
110 120 130 140 150
VEGLKAVAAG MNPMDLKRGI DKAVAEAVKT LHAISKPCSD SKAIAQVGTI
160 170 180 190 200
SANSDETVGA KIAEAMEKVG KEGVITVEEG QGLEDSLEVV EGMQFDRGYL
210 220 230 240 250
SPYFINNQQS QQVELENPYI LLHDKKIANI RDMLPLLEGV AKSGQPLLIV
260 270 280 290 300
AEDVEGEALA TLVINSMRGI VKVAAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEEVGLTLE SVTLDQLGTA KRVTVGKDNT TIIDGSGEKS AIEARVALIR
360 370 380 390 400
HQIEESSSDY DKEKLQERVA KLAGGVAVIK VGAATEVEMK EKKDRVEDAL
410 420 430 440 450
HATRAAVEEG IVPGGGVALI RAINSIVDLK GDNYDQQVGI DIARRAMEYP
460 470 480 490 500
LRTIVSNAGS EAAVVLERVK SGKGNDGYDA ATGQYVDMVA AGIIDPTKVT
510 520 530 540
RSALQNAASV AGLMITTEAM VSEIPQKEEG HHHDMGGMGG MGGMGMM
Length:547
Mass (Da):57,629
Last modified:June 12, 2007 - v1
Checksum:i0915859C0676E504
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000513 Genomic DNA. Translation: ABQ13553.1.
RefSeqiWP_012031623.1. NC_009446.1.

Genome annotation databases

EnsemblBacteriaiABQ13553; ABQ13553; DNO_1339.
KEGGidno:DNO_1339.

Similar proteinsi

Entry informationi

Entry nameiCH60_DICNV
AccessioniPrimary (citable) accession number: A5EX17
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: October 25, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families