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A5EVU0 (ACKA_DICNV) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:DNO_0447
OrganismDichelobacter nodosus (strain VCS1703A) [Complete proteome] [HAMAP]
Taxonomic identifier246195 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Cardiobacteriales › Cardiobacteriaceae › Dichelobacter

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Acetate kinase HAMAP MF_00020
PRO_1000057185

Sequences

Sequence LengthMass (Da)Tools
A5EVU0 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 322CAB3D1F803ECD

FASTA39442,941
        10         20         30         40         50         60 
MQFVLVLNCG SSSLKFAVMN PTSGDVLLNG TAERLGHDVG SLTVKDESGK AVQEIKPGTH 

        70         80         90        100        110        120 
AQALELIVET LKTKNLMDKI AAVGHRLVHG GEFFKESVVI NNEVREKVAE CIRLAPLHNP 

       130        140        150        160        170        180 
ANITGIEAAL KVFPKLPQVG VFDTAFHQQM PEKAYLYPLP RKFYEEFHIR RYGFHGTSFR 

       190        200        210        220        230        240 
YIASQLESVT GLKNPRTVVC HLGNGGSLAA IKDGHSVDTT MGLTPLEGIV HGTRCGDIDP 

       250        260        270        280        290        300 
AIIQILQKQF HISATEMNEI LWKKSGLLGL SGISNDCRSL EEAMAEGNEA AIRALEVYCY 

       310        320        330        340        350        360 
RLAKHIAAQM VALNGCDALV FTGGIGENSA FVRANTMEQL AFLGFELDKK ANEETSRGKQ 

       370        380        390 
GKISTANSKP VWVIPTNEEL LIARDTAQLS GMTR

« Hide

References

[1]"Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus."
Myers G.S.A., Parker D., Al-Hasani K., Kennan R.M., Seemann T., Ren Q., Badger J.H., Selengut J.D., Deboy R.T., Tettelin H., Boyce J.D., McCarl V.P., Han X., Nelson W.C., Madupu R., Mohamoud Y., Holley T., Fedorova N. expand/collapse author list , Khouri H., Bottomley S.P., Whittington R.J., Adler B., Songer J.G., Rood J.I., Paulsen I.T.
Nat. Biotechnol. 25:569-575(2007) [PubMed: 17468768] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: VCS1703A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000513 Genomic DNA. Translation: ABQ13779.1.
RefSeqYP_001209361.1. NC_009446.1.

3D structure databases

ProteinModelPortalA5EVU0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5EVU0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5123454.
GenomeReviewsGene locus DNO_0447 in contig CP000513_GR.
KEGGdno:DNO_0447.
PATRIC21785200. VBIDicNod48475_0445.
TIGRDNO_0447.

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMASVIINDE.

Enzyme and pathway databases

BioCycDNOD246195:DNO_0447-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_DICNV
AccessionPrimary (citable) accession number: A5EVU0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 12, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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