Reviewed, UniProtKB/Swiss-Prot A5EV42 (SYGA_DICNV)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	DNO_0701

Organism

Dichelobacter nodosus (strain VCS1703A) [Complete proteome] [HAMAP]

Taxonomic identifier

246195 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Cardiobacteriales › Cardiobacteriaceae › Dichelobacter

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 299	299	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000101184

Sequences

	Sequence		Length	Mass (Da)
	A5EV42-1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 89F48795E16198CF	FASTA	299	34,382
	10 20 30 40 50 60 MLSFQDMILT LQRFWIKHGC ALMQPYDMEV GAGTFHESTF LRAIGPEPWR AIFVQASRRP 70 80 90 100 110 120 SDGRYGENPN RLQRYYQMQV VIKPSAPDLQ ALYLQSLYAI GIDPATQDIR FVEDNWESPT 130 140 150 160 170 180 LGAWGLGWEV WLNGMEISQF TYFQQVGGIE CKPVTGELTY GLERIAMYLQ NVNSVYDLIW 190 200 210 220 230 240 TTTPDGVLTY GDVHQQNERE QSFYNFEYAD IADLCAQFDA AEKMSLLLAQ KKFPLPAYEQ 250 260 270 280 290 ALKASHLFNL LDARRAISVT ERQRYILRVR ALSKAAAEAW YETRAALDFP LCRQQGIEK

References

[1]

"Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus." Myers G.S.A., Parker D., Al-Hasani K., Kennan R.M., Seemann T., Ren Q., Badger J.H., Selengut J.D., Deboy R.T., Tettelin H., Boyce J.D., McCarl V.P., Han X., Nelson W.C., Madupu R., Mohamoud Y., Holley T., Fedorova N. , Khouri H., Bottomley S.P., Whittington R.J., Adler B., Songer J.G., Rood J.I., Paulsen I.T. Nat. Biotechnol. 25:569-575(2007) [PubMed: 17468768] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000513 Genomic DNA. Translation: ABQ14314.1.
RefSeq	YP_001209610.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5EV42.
Genome annotation databases
GeneID	5122684.
GenomeReviews	Gene locus DNO_0701 in contig CP000513_GR.
KEGG	dno:DNO_0701.
TIGR	DNO_0701.
Phylogenomic databases
OMA	CRRPTDG.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DICNV

Accession

Primary (citable) accession number: A5EV42

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	June 12, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)