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A5EU53 (A5EU53_BRASB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401
Gene names
Name:msrA EMBL ABQ39697.1
Synonyms:msrA2 HAMAP MF_01401
Ordered Locus Names:BBta_7872
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP] EMBL ABQ39697.1
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site541 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
A5EU53 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 040A6533253533FF

FASTA21823,448
        10         20         30         40         50         60 
MFFMRKSPVL PTAADALPGR TQPIPTAPTH FVNGRRLLPP YPAGLEQAVF GLGCFWGAER 

        70         80         90        100        110        120 
KFWQLGDGVH VTAVGYAGGH TPNPTYEEVC SGLTAHTEVV LVVFDPKVIS YERLLKTFWE 

       130        140        150        160        170        180 
SHDPTQGMRQ GNDVGTQYRS AIYTFSDAQR ETADASKAAY ETALRAKGLG AITTEIAPAG 

       190        200        210 
PFYFAEDYHQ QYLAKNPAGY CGLGGTGVAC PIGVGVTA 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000494 Genomic DNA. Translation: ABQ39697.1.
RefSeqYP_001243603.1. NC_009485.1.

3D structure databases

ProteinModelPortalA5EU53.
SMRA5EU53. Positions 15-211.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5EU53.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5152167.
GenomeReviewsGene locus BBta_7872 in contig CP000494_GR.
KEGGbbt:BBta_7872.
PATRIC21216319. VBIBraSp29847_7806.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMASAIYCTT.
ProtClustDBPRK00058.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5EU53_BRASB
AccessionPrimary (citable) accession number: A5EU53
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)