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A5ETC5 (AROB_BRASB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:BBta_7572
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP]
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3823823-dehydroquinate synthase HAMAP MF_00110
PRO_1000094463

Sequences

Sequence LengthMass (Da)Tools
A5ETC5 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: F1E396171EC750A1

FASTA38240,246
        10         20         30         40         50         60 
MTAPLKTFDP IIVDVALGER AYDIVIGRGV LASLGQRIAA LRPGVRTAIV TDRTVAAHWL 

        70         80         90        100        110        120 
KPTEAILAEA GIPSSTIVVE EGEGSKTYAG LEKVSEALIA AKIERNDLVI ALGGGVVGDL 

       130        140        150        160        170        180 
AGFAAAILRR GVNFVQVPTS LLAQVDSSVG GKTGINSPQG KNLLGAFHQP VLVIADTAVL 

       190        200        210        220        230        240 
DTLSPRQFRA GYAEVAKYGL LGDAGFFTWL EANHADIVTG GAAREHAVAT SCRAKAAIVA 

       250        260        270        280        290        300 
RDERETGDRA LLNLGHTFGH ALEAITGFSD RLFHGEGVAV GMVLAAQFSA ELGMLPPDDV 

       310        320        330        340        350        360 
TRIERHLAAV GLPTHLQDIA GFAQEGIGDA DRLLALMAQD KKVKRGKLTF ILMEAIGRAV 

       370        380 
IAKDVDPARV RDFLQAKLHR RG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000494 Genomic DNA. Translation: ABQ39419.1.
RefSeqYP_001243325.1. NC_009485.1.

3D structure databases

ProteinModelPortalA5ETC5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5ETC5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5155541.
GenomeReviewsGene locus BBta_7572 in contig CP000494_GR.
KEGGbbt:BBta_7572.
PATRIC21215743. VBIBraSp29847_7519.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BRASB
AccessionPrimary (citable) accession number: A5ETC5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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