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A5ESQ5

- TRUA_BRASB

UniProt

A5ESQ5 - TRUA_BRASB

Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    • Comment

    Functioni

    Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei52 – 521NucleophileUniRule annotation
    Binding sitei111 – 1111SubstrateUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciBSP288000:GJBR-7039-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(38-40) synthaseUniRule annotation
    tRNA pseudouridylate synthase IUniRule annotation
    tRNA-uridine isomerase IUniRule annotation
    Gene namesi
    Name:truAUniRule annotation
    Ordered Locus Names:BBta_7335
    OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
    Taxonomic identifieri288000 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
    ProteomesiUP000000246: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 245245tRNA pseudouridine synthase APRO_1000017045Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi288000.BBta_7335.

    Structurei

    3D structure databases

    ProteinModelPortaliA5ESQ5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0101.
    HOGENOMiHOG000248672.
    KOiK06173.
    OMAiYLTKVEY.
    OrthoDBiEOG6Z9B4R.

    Family and domain databases

    Gene3Di3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPiMF_00171. TruA.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view]
    PANTHERiPTHR11142. PTHR11142. 1 hit.
    PfamiPF01416. PseudoU_synth_1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5ESQ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRYKLTIEY DGTPFCGWQL QETLPSVQGA LEAAVQATCG VPTRVHGSGR    50
    TDAGVHATGQ VAHCDIAKDF RPDKLRDALN AHLRPNPVAV LEAEIVSDTF 100
    EARFSARKRH YRYRIVNRRS NLALEVGRVW RVPQRLDSDA MHAAAQRLIG 150
    RHDFTTFRDT ECQAKSPEKT LDQLDVVRDG DAVTILTSAR SYLHSQVRSM 200
    VGSLVWVGQG RWSADDLAAA LAARNRAACG VVAPPEGLYL VKVDY 245
    Length:245
    Mass (Da):27,106
    Last modified:June 12, 2007 - v1
    Checksum:i514623A7F177EC83
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000494 Genomic DNA. Translation: ABQ39199.1.
    RefSeqiWP_012047102.1. NC_009485.1.
    YP_001243105.1. NC_009485.1.

    Genome annotation databases

    EnsemblBacteriaiABQ39199; ABQ39199; BBta_7335.
    GeneIDi5149518.
    KEGGibbt:BBta_7335.
    PATRICi21215295. VBIBraSp29847_7296.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000494 Genomic DNA. Translation: ABQ39199.1 .
    RefSeqi WP_012047102.1. NC_009485.1.
    YP_001243105.1. NC_009485.1.

    3D structure databases

    ProteinModelPortali A5ESQ5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 288000.BBta_7335.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ39199 ; ABQ39199 ; BBta_7335 .
    GeneIDi 5149518.
    KEGGi bbt:BBta_7335.
    PATRICi 21215295. VBIBraSp29847_7296.

    Phylogenomic databases

    eggNOGi COG0101.
    HOGENOMi HOG000248672.
    KOi K06173.
    OMAi YLTKVEY.
    OrthoDBi EOG6Z9B4R.

    Enzyme and pathway databases

    BioCyci BSP288000:GJBR-7039-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPi MF_00171. TruA.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view ]
    PANTHERi PTHR11142. PTHR11142. 1 hit.
    Pfami PF01416. PseudoU_synth_1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BTAi1 / ATCC BAA-1182.

    Entry informationi

    Entry nameiTRUA_BRASB
    AccessioniPrimary (citable) accession number: A5ESQ5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3