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A5ESQ2

- DAPD_BRASB

UniProt

A5ESQ2 - DAPD_BRASB

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Protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Gene
dapD, BBta_7332
Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei108 – 1081Substrate By similarity
Binding sitei145 – 1451Substrate By similarity

GO - Molecular functioni

  1. 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. diaminopimelate biosynthetic process Source: UniProtKB-HAMAP
  2. lysine biosynthetic process via diaminopimelate Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Diaminopimelate biosynthesis, Lysine biosynthesis

Enzyme and pathway databases

BioCyciBSP288000:GJBR-7036-MONOMER.
UniPathwayiUPA00034; UER00019.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC:2.3.1.117)
Alternative name(s):
Tetrahydrodipicolinate N-succinyltransferase
Short name:
THDP succinyltransferase
Short name:
THP succinyltransferase
Short name:
Tetrahydropicolinate succinylase
Gene namesi
Name:dapD
Ordered Locus Names:BBta_7332
OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Taxonomic identifieri288000 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000000246: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2812812,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferaseUniRule annotation
PRO_1000047120Add
BLAST

Proteomic databases

PRIDEiA5ESQ2.

Interactioni

Subunit structurei

Homotrimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi288000.BBta_7332.

Structurei

3D structure databases

ProteinModelPortaliA5ESQ2.
SMRiA5ESQ2. Positions 3-281.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG2171.
HOGENOMiHOG000003295.
KOiK00674.
OMAiYIARNTV.
OrthoDBiEOG68H8BV.

Family and domain databases

Gene3Di1.10.166.10. 1 hit.
HAMAPiMF_00811. DapD.
InterProiIPR005664. DapD_Trfase_Hexpep_rpt_fam.
IPR001451. Hexapep_transf.
IPR023180. THP_succinylTrfase_dom1.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PANTHERiPTHR19136:SF52. PTHR19136:SF52. 1 hit.
PfamiPF00132. Hexapep. 1 hit.
PF14805. THDPS_N_2. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
TIGRFAMsiTIGR00965. dapD. 1 hit.

Sequencei

Sequence statusi: Complete.

A5ESQ2-1 [UniParc]FASTAAdd to Basket

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MSLSALESTI NSAFDARDGV STTTKGEIRD AVESALELLD KGEARVAERG    50
TDGTWSVNQW LKKAVLLSFR LNDMSVIPGG PGQASWWDKV PSKFEGWGEN 100
RFREAGFRAV PGAIVRRSAF IAKNVVLMPS FVNLGAYVDE ATMVDTWSTV 150
GSCAQIGKRV HISGGVGIGG VLEPLQAGPV IIEDDCFIGA RSEVAEGVVV 200
RKGAVLAMGV FLGASTKVID RETGETFVGE VPEYAVVVPG ALPGKPMKNG 250
QIGPSTACAV IVKRVDERTR SKTSINELLR D 281
Length:281
Mass (Da):29,880
Last modified:June 12, 2007 - v1
Checksum:iEE8F4B53BAC8E440
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000494 Genomic DNA. Translation: ABQ39196.1.
RefSeqiWP_012047099.1. NC_009485.1.
YP_001243102.1. NC_009485.1.

Genome annotation databases

EnsemblBacteriaiABQ39196; ABQ39196; BBta_7332.
GeneIDi5149515.
KEGGibbt:BBta_7332.
PATRICi21215289. VBIBraSp29847_7293.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000494 Genomic DNA. Translation: ABQ39196.1 .
RefSeqi WP_012047099.1. NC_009485.1.
YP_001243102.1. NC_009485.1.

3D structure databases

ProteinModelPortali A5ESQ2.
SMRi A5ESQ2. Positions 3-281.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 288000.BBta_7332.

Proteomic databases

PRIDEi A5ESQ2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ39196 ; ABQ39196 ; BBta_7332 .
GeneIDi 5149515.
KEGGi bbt:BBta_7332.
PATRICi 21215289. VBIBraSp29847_7293.

Phylogenomic databases

eggNOGi COG2171.
HOGENOMi HOG000003295.
KOi K00674.
OMAi YIARNTV.
OrthoDBi EOG68H8BV.

Enzyme and pathway databases

UniPathwayi UPA00034 ; UER00019 .
BioCyci BSP288000:GJBR-7036-MONOMER.

Family and domain databases

Gene3Di 1.10.166.10. 1 hit.
HAMAPi MF_00811. DapD.
InterProi IPR005664. DapD_Trfase_Hexpep_rpt_fam.
IPR001451. Hexapep_transf.
IPR023180. THP_succinylTrfase_dom1.
IPR011004. Trimer_LpxA-like.
[Graphical view ]
PANTHERi PTHR19136:SF52. PTHR19136:SF52. 1 hit.
Pfami PF00132. Hexapep. 1 hit.
PF14805. THDPS_N_2. 1 hit.
[Graphical view ]
SUPFAMi SSF51161. SSF51161. 1 hit.
TIGRFAMsi TIGR00965. dapD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BTAi1 / ATCC BAA-1182.

Entry informationi

Entry nameiDAPD_BRASB
AccessioniPrimary (citable) accession number: A5ESQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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