Reviewed,
UniProtKB/Swiss-Prot A5EPK0 (MURB_BRASB)
Last modified
November 3, 2009.
Version 24.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: UDP-N-acetylenolpyruvoylglucosamine reductase EC=1.1.1.158 Alternative name(s): UDP-N-acetylmuramate dehydrogenase | ||||
| Gene names |
| ||||
| Organism | Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 288000 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium |
Protein attributes
| Sequence length | 307 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Cell wall formation By similarity. |
| Catalytic activity | UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH. HAMAP MF_00037 |
| Cofactor | FAD By similarity. |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00037 |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the murB family. Contains 1 FAD-binding PCMH-type domain. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 307 | 307 | UDP-N-acetylenolpyruvoylglucosamine reductase HAMAP MF_00037 | PRO_1000002864 | |||||
Regions | |||||||||
| Domain | 34 – 199 | 166 | FAD-binding PCMH-type | ||||||
Sites | |||||||||
| Active site | 179 | 1 | By similarity | ||||||
| Active site | 228 | 1 | Proton donor By similarity | ||||||
| Active site | 298 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. Sadowsky M.Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000494 Genomic DNA. Translation: ABQ38094.1. | |
| RefSeq | YP_001242000.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A5EPK0. |
Genome annotation databases | |
| GeneID | 5152034. |
| GenomeReviews | Gene locus BBta_6170 in contig CP000494_GR. |
| KEGG | bbt:BBta_6170. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| OMA | QPIREKT. |
Family and domain databases | |
| HAMAP | MF_00037. [Tree] |
| InterPro | IPR016169. CO_DH_flavot_FAD-bd_sub2. IPR016166. FAD-bd_2. IPR016167. FAD-bd_2_sub1. IPR003170. MurB. IPR011601. MurB_C. IPR006094. Oxid_FAD_bind_N. [Graphical view] |
| Gene3D | G3DSA:3.30.465.10. CO_DH_flavoprot_FAD-bd_sub2. 1 hit. G3DSA:3.30.43.10. FAD-binding_2_sub1. 1 hit. |
| PANTHER | PTHR21071. MurB. 1 hit. |
| Pfam | PF01565. FAD_binding_4. 1 hit. PF02873. MurB_C. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00179. murB. 1 hit. |
| PROSITE | PS51387. FAD_PCMH. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MURB_BRASB | ||||||||
| Accession | Primary (citable) accession number: A5EPK0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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