Reviewed, UniProtKB/Swiss-Prot A5EK25 (TRPC_BRASB)

Names and origin

Protein names

Recommended name:
    Indole-3-glycerol phosphate synthase
      Short name=IGPS
    EC=4.1.1.48

Gene names

Name:	trpC
Ordered Locus Names:	BBta_4483

Organism

Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP]

Taxonomic identifier

288000 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the trpC family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Indole-3-glycerol phosphate synthase HAMAP MF_00134		PRO_1000018446

Sequences

	Sequence		Length	Mass (Da)
	A5EK25-1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: FF05472021F02D66	FASTA	272	29,137
	10 20 30 40 50 60 MSDILAKIEA YKREEIAAAK RACPLAELEA RARDASPPRG FVAAIRNKHA NGDYALIAEV 70 80 90 100 110 120 KKASPSKGLI RADFDPPVLA RAYQAGGAAC LSVLTDTPSF QGHLEFMVAA RSATTLPVLR 130 140 150 160 170 180 KDFLFDTYQV AEARAHGADC ILIIMAALDD AAAADIEAAA LDSGMDVLIE IHDRDELDRA 190 200 210 220 230 240 LKLRSPMIGI NNRNLRTFET TLATSEALAP LVPKERLLVG ESGIFTPADL TRLARVDIQT 250 260 270 FLVGESLMRQ ADVTAATRAL LARDASPASA AE

References

[1]

"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. , Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M. Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000494 Genomic DNA. Translation: ABQ36519.1.
RefSeq	YP_001240425.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5EK25.
Genome annotation databases
GeneID	5155190.
GenomeReviews	Gene locus BBta_4483 in contig CP000494_GR.
KEGG	bbt:BBta_4483.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LRSPMIG.
Family and domain databases
HAMAP	MF_00134. [Tree]
InterPro	IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GPS_central. [Graphical view]
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
ProDom	PD001511. IGPS. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPC_BRASB

Accession

Primary (citable) accession number: A5EK25

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 12, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)