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A5EJW7 (SYR_BRASB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BBta_4423
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP]
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length598 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 598598Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000017993

Regions

Motif139 – 14911"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A5EJW7 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 210EFB09ACDA0E56

FASTA59866,027
        10         20         30         40         50         60 
MLEQASNLHL FADVLARVHA ICAALAKDGN WPEGIDVSRV VVEPPRDPSH GDMATNAAMV 

        70         80         90        100        110        120 
LAKEAKAKPR DLAEAIAERL RADELVAKVD VAGPGFINLT LHPVVWARQL GTILRDGDAY 

       130        140        150        160        170        180 
GRIAPVVGAP KVNVEYVSAN PTGPMHVGHC RGAVFGDALC SLLQFAGRDV TREYYINDAG 

       190        200        210        220        230        240 
AQVDVLARSA FLRYREALGE EIGAIPEGLY PGDYLKPVGQ ALAAEHGDRL KAMPEAQWLP 

       250        260        270        280        290        300 
IVRDKAIAMM MAEIKDDLAA LNIRHDVFFS ERSLIAGSTN KVAETIEFLR ERGDVYEGRL 

       310        320        330        340        350        360 
PPPKGAPVED WEDREQLLFR ATAYGDDVDR PLIKSDGSYT YFASDIANHR HKFERGFADL 

       370        380        390        400        410        420 
IDVFGADHGG YIKRMQAAVK AVTAAQAVLD VKVVQLVKLL RNGEPVKMSK RSGDFVTLRE 

       430        440        450        460        470        480 
VVDEVGRDAV RFMMLYRKND AVLDFDLAKV IEQSRDNPVF YVQYGHARGH SIFRNARDSF 

       490        500        510        520        530        540 
PSLPVEEGAR LAFLRQAKLE KLADPSEIDL LKRLALYPRT VESAALAHEP HRVAFYLYDL 

       550        560        570        580        590 
ASEFHALWTR GRDLPYLRFI IDDDAELTMA RLAMVQGVVS VLASGLAILG VNAPDAMR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000494 Genomic DNA. Translation: ABQ36461.1.
RefSeqYP_001240367.1. NC_009485.1.

3D structure databases

ProteinModelPortalA5EJW7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING288000.BBta_4423.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ36461; ABQ36461; BBta_4423.
GeneID5153868.
KEGGbbt:BBta_4423.
PATRIC21209597. VBIBraSp29847_4466.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMALCNVLAK.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycBSP288000:GJBR-4221-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BRASB
AccessionPrimary (citable) accession number: A5EJW7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries