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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:BBta_3153
OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Taxonomic identifieri288000 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000000246 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000468481 – 376Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST376

Interactioni

Protein-protein interaction databases

STRINGi288000.BBta_3153

Structurei

3D structure databases

ProteinModelPortaliA5EGH4
SMRiA5EGH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

A5EGH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTETADPLNR PLKRGWTTGS CATAAARAAY ELLMTGSCPA IVDIALPGGR
60 70 80 90 100
RASFAVAIHE AEGGRATAGV VKDAGDDPDV THGALIKATV QRRDAGSGIA
110 120 130 140 150
FRAGSGVGTV TRPGLPLPPG EPAINPVPRE MIIAAIDEAA TALGGTRDVT
160 170 180 190 200
VEIAIPGGED LAKKTLNPRL GIVGGLSILG TTGIVVPFSC AAWIHSIYRG
210 220 230 240 250
IDVARAAGLP HIAGATGSTS EKAVQQLYGL PDTALIDMGD FAGGMLKYLR
260 270 280 290 300
RHPVGRVTVA GGFAKMTKLG QGLLDLHSRA GEVDLGWLAT ALHDAGAPPE
310 320 330 340 350
LVETARTANT ALQVLQESDR SGFPAGDVVA RAAWQTAYRA LANDAVALDV
360 370
AVFDRDGRLV GRCLGADHSP LPRNRR
Length:376
Mass (Da):38,755
Last modified:June 12, 2007 - v1
Checksum:iB7E6B8DAAF3DDB93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000494 Genomic DNA Translation: ABQ35268.1
RefSeqiWP_012043286.1, NC_009485.1

Genome annotation databases

EnsemblBacteriaiABQ35268; ABQ35268; BBta_3153
KEGGibbt:BBta_3153

Similar proteinsi

Entry informationi

Entry nameiCBID_BRASB
AccessioniPrimary (citable) accession number: A5EGH4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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